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Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)

文献类型：期刊论文

作者Ma, Xiaofang1; Zhang, Yingying1; Liu, Bin1; Yang, Jiahui1,2; Hu, Kaifeng1
刊名BIOMOLECULAR NMR ASSIGNMENTS
出版日期2018-04-01
卷号12期号:1页码:145-148
关键词Ror1 Kringle Nmr
ISSN号1874-2718
DOI10.1007/s12104-017-9797-9
英文摘要

Receptor tyrosine kinase-like orphan receptor 1 (ROR1) expresses at high level in many cancers and has been suggested as a potential therapeutic target. It was reported that the Kringle (KNG) domain of ROR1 extracellular region is involved in ROR1/ROR2 heterooligomerization. Monoantibodies that target KNG domain of ROR1 could induce apoptosis of chronic lymphocytic leukemia cells. Here we present the backbone and side chain assignments of KNG domain of ROR1, which lays a foundation for its further structural and function research.

语种英语
WOS记录号WOS:000428448100028
源URL[http://ir.kib.ac.cn/handle/151853/60514]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China
2.Chengdu Univ TCM, Sch Basic Med, 1166 Liutai Ave, Chengdu 611137, Sichuan, Peoples R China
推荐引用方式
GB/T 7714		 Ma, Xiaofang,Zhang, Yingying,Liu, Bin,et al. Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)[J]. BIOMOLECULAR NMR ASSIGNMENTS,2018,12(1):145-148.
APA Ma, Xiaofang,Zhang, Yingying,Liu, Bin,Yang, Jiahui,&Hu, Kaifeng.(2018).Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1).BIOMOLECULAR NMR ASSIGNMENTS,12(1),145-148.
MLA Ma, Xiaofang,et al."Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)".BIOMOLECULAR NMR ASSIGNMENTS 12.1(2018):145-148.

入库方式： OAI收割

来源：昆明植物研究所

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