A new epipolythiodioxopiperazine with antibacterial and cytotoxic activities from the endophytic fungus Chaetomium sp M336
文献类型：期刊论文
| 作者 | Yu, Fei-Xue1,2,3; Chen, Yao3; Yang, Yin-He4; Li, Guo-Hong1,2; Zhao, Pei-Ji1,2,4 |
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2018 |
| 卷号 | 32期号:6页码:689-694 |
| 关键词 | Chaetomium Sp M336 Chemical Constituents Structure Identification 6-formamide-chetomin Cytotoxicity Antibacterial Activities |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786419.2017.1338285 |
| 英文摘要 | A new compound 6-formamide-chetomin (1) together with chetomin (2) was isolated from solid fermentation products of the endophytic fungus Chaetomium sp. M336, which were elucidated by extensive spectroscopic analyses, including 1D and 2D NMR, and HR-ESI-MS experiments. The bioassay result showed that compound 1 had strong antibacterial activity against Escherichia coli, Staphylococcus aureus, Salmonella typhimurium ATCC 6539 and Enterococcus faecalis with minimum inhibitory concentration (MIC) value of 0.78 mu g/mL; meanwhile it exhibited strong cytotoxicity with IC50 values of 21.627.1 nM against cell lines HeLa, SGC-7901 and A549. |
| 语种 | 英语 |
| WOS记录号 | WOS:000426942800010 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/60529]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Yunnan Univ, Minist Educ, State Key Lab Conservat & Utilizat Bioresources Y, Kunming, Yunnan, Peoples R China 2.Yunnan Univ, Minist Educ, Key Lab Microbial Resources, Kunming, Yunnan, Peoples R China 3.Kunming Univ Sci & Technol, Fac Med, Kunming, Yunnan, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Fei-Xue,Chen, Yao,Yang, Yin-He,et al. A new epipolythiodioxopiperazine with antibacterial and cytotoxic activities from the endophytic fungus Chaetomium sp M336[J]. NATURAL PRODUCT RESEARCH,2018,32(6):689-694. |
| APA | Yu, Fei-Xue,Chen, Yao,Yang, Yin-He,Li, Guo-Hong,&Zhao, Pei-Ji.(2018).A new epipolythiodioxopiperazine with antibacterial and cytotoxic activities from the endophytic fungus Chaetomium sp M336.NATURAL PRODUCT RESEARCH,32(6),689-694. |
| MLA | Yu, Fei-Xue,et al."A new epipolythiodioxopiperazine with antibacterial and cytotoxic activities from the endophytic fungus Chaetomium sp M336".NATURAL PRODUCT RESEARCH 32.6(2018):689-694. |
入库方式： OAI收割
来源：昆明植物研究所
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