Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions
文献类型：期刊论文
| 作者 | Zhao, Longyan1,2 ; Qin, Yujing1; Guan, Ruowei1; Zheng, Wenqi1; Liu, Jikai1,2; Zhao, Jinhua1,2,3
|
| 刊名 | CARBOHYDRATE POLYMERS
 |
| 出版日期 | 2018-04-15 |
| 卷号 | 186页码:217-225 |
| 关键词 | Sea Cucumber Polysaccharide Fucosylated Glycosaminoglycan In Vitro Digestion Digestive Enzyme |
| ISSN号 | 0144-8617 |
| DOI | 10.1016/j.carbpol.2018.01.029 |
| 英文摘要 | The digestibility of fucosylated glycosaminoglycan (FG) and its effects on digestive enzymes were investigated using an in vitro digestion model. Results showed that the molecular weight and the reducing sugar content of FG were not significantly changed, and no free monosaccharides released from FG were detected after the salivary, gastric and intestinal digestion, indicating that both the backbone and the sulfated fucose branches of FG are resistant to be cleaved in the saliva and gastrointestinal tract environments. Furthermore, FG can dose-dependently inhibit digestive enzymes such as alpha-amylase, pepsin and pancreatic lipase in different degrees under the simulated digestion conditions due to the sulfate and carboxyl groups. These physiological effects of FG may help control the postprandial glucose concentration and have the potential in the prevention or treatment of reflux disease and obesity. The findings may provide information on the digestibility and beneficial physiological effects of FG as a potential natural product to promote human health. |
| 语种 | 英语 |
| WOS记录号 | WOS:000426360800025 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/60538]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China 2.South Cent Univ Nationalities, Natl Demonstrat Ctr Expt Ethnopharmacol Educ, Wuhan 430074, Hubei, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Longyan,Qin, Yujing,Guan, Ruowei,et al. Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions[J]. CARBOHYDRATE POLYMERS,2018,186:217-225. |
| APA | Zhao, Longyan,Qin, Yujing,Guan, Ruowei,Zheng, Wenqi,Liu, Jikai,&Zhao, Jinhua.(2018).Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions.CARBOHYDRATE POLYMERS,186,217-225. |
| MLA | Zhao, Longyan,et al."Digestibility of fucosylated glycosaminoglycan from sea cucumber and its effects on digestive enzymes under simulated salivary and gastrointestinal conditions".CARBOHYDRATE POLYMERS 186(2018):217-225. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。