Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid
文献类型:期刊论文
作者 | Guo, Jing-jing1,2; Yang, Bi-juan2,3; Jing, Chen-xu2; Chen, Duo-zhi2; Hao, Xiao-jiang2![]() |
刊名 | JOURNAL OF CHEMICAL RESEARCH
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出版日期 | 2017-04-01 |
期号 | 4页码:202-204 |
关键词 | Amaryllidaceae Alkaloid Palladium Catalyst Aryl-aryl Coupling N-aryl Coupling |
ISSN号 | 1747-5198 |
DOI | 10.3184/174751917X14894997017496 |
英文摘要 | Ismine (6-[2-( methylamino) phenyl]-1,3-benzodioxole-5-methanol, 1), a biologically active alkaloid, has been synthesised by a rapid and simple four-step sequence. This synthesis involved a consecutive aryl-aryl and N-aryl coupling, leading to a phenanthridine derivative in a one-pot sequence, which employed a palladium catalyst and trifurylphosphine as the ligand. This synthesis gave an overall yield of 23%. |
语种 | 英语 |
WOS记录号 | WOS:000416040700004 |
源URL | [http://ir.kib.ac.cn/handle/151853/60632] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Yunnan Univ Tradit Chinese Med, Coll Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 3.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650000, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Guo, Jing-jing,Yang, Bi-juan,Jing, Chen-xu,et al. Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid[J]. JOURNAL OF CHEMICAL RESEARCH,2017(4):202-204. |
APA | Guo, Jing-jing,Yang, Bi-juan,Jing, Chen-xu,Chen, Duo-zhi,&Hao, Xiao-jiang.(2017).Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid.JOURNAL OF CHEMICAL RESEARCH(4),202-204. |
MLA | Guo, Jing-jing,et al."Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid".JOURNAL OF CHEMICAL RESEARCH .4(2017):202-204. |
入库方式: OAI收割
来源:昆明植物研究所
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