NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis
文献类型:期刊论文
作者 | Zeng, Guang-Zhi3,4; Wang, Zhe1,2,3![]() |
刊名 | JOURNAL OF ETHNOPHARMACOLOGY
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出版日期 | 2018-06-28 |
卷号 | 220页码:220-227 |
关键词 | Rubiarbonol g Rubia Yunnanensis Cytotoxicity Mechanism |
ISSN号 | 0378-8741 |
DOI | 10.1016/j.jep.2017.10.026 |
英文摘要 | Ethnopharmacological relevance: Rubia yunnanensis is a medicinal plant mainly grown in Yunnan province in Southwest China, and its root named "Xiaohongshen" has been used as a herb in Yunnan for the treatment of cancers. Three major types of chemical components, Rubiaceae-type cyclopeptides, quinones, and triterpenoids, were identified from R. yunnanensis, in which some of compounds including rubiarbonol G (RG), a unique arboriane-type triterpenoid, showed cytotoxicity on cancer cells. But the cytotoxic mechanism of RG has not been reported. |
语种 | 英语 |
源URL | [http://ir.kib.ac.cn/handle/151853/61370] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.China Pharmaceut Univ, Sch Tradit Chinese Pharm, Nanjing 211198, Jiangsu, Peoples R China 2.China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 211198, Jiangsu, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 4.Yunnan Minzu Univ, YMU HKBU Joint Lab Tradit Nat Med, Kunming 650500, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Zeng, Guang-Zhi,Wang, Zhe,Zhao, Li-Mei,et al. NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis[J]. JOURNAL OF ETHNOPHARMACOLOGY,2018,220:220-227. |
APA | Zeng, Guang-Zhi,Wang, Zhe,Zhao, Li-Mei,Fan, Jun-Ting,&Tan, Ning-Hua.(2018).NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.JOURNAL OF ETHNOPHARMACOLOGY,220,220-227. |
MLA | Zeng, Guang-Zhi,et al."NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis".JOURNAL OF ETHNOPHARMACOLOGY 220(2018):220-227. |
入库方式: OAI收割
来源:昆明植物研究所
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