Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS
文献类型：期刊论文
| 作者 | Tang, Li1; Liu, Ying1; Wang, Yeling1; Long, Chunlin1,2 |
| 刊名 | JOURNAL OF NATURAL MEDICINES
 |
| 出版日期 | 2010-04-01 |
| 卷号 | 64期号:2页码:182-186 |
| ISSN号 | 1340-3443 |
| 关键词 | Radix Astragali Antiviral Activity Flavonoid Saponin Hplc-dad-esi-ms/ms |
| DOI | 10.1007/s11418-009-0381-1 |
| 通讯作者 | tangli1973@yahoo.com.cn |
| 文献子类 | Article |
| 英文摘要 | Radix astragali (Huangqi in Chinese) is a well-known traditional Chinese medicinal herb that has been used clinically in China for centuries to cure various diseases. To profile the antiviral constituents of this herb, a high-performance liquid chromatography-diode array detector-electrospray ionization-tandem mass spectrometry (HPLC-DAD-ESI-MS/MS) analytical method was developed to separate and determinate the active part of the extract of Radix astragali, which showed potent inhibition of several viruses. By comparing their retention time and MS data with those obtained from the authentic compounds and the published data, a total of 18 compounds, comprising 11 flavonoids and 7 saponins, were identified. This study provides an approach to rapidly characterize bioactive constituents in traditional Chinese medicines (TCMs). |
| 学科主题 | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| WOS关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY ; TANDEM MASS-SPECTROMETRY ; LC-MS ; ISOFLAVONOIDS ; ARRAY ; CONSTITUENTS ; MONGHOLICUS ; EXTRACTION ; PRODUCTS ; TANG |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000275691600010 |
| 资助机构 | This work was supported by Beijing Nova Program (2008118), 985 Project (CUN 985-03-03) and 111Project (B08044). |
| 公开日期 | 2011-12-06 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/2315]  |
| 专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tang, Li,Liu, Ying,Wang, Yeling,et al. Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS[J]. JOURNAL OF NATURAL MEDICINES,2010,64(2):182-186. |
| APA | Tang, Li,Liu, Ying,Wang, Yeling,&Long, Chunlin.(2010).Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS.JOURNAL OF NATURAL MEDICINES,64(2),182-186. |
| MLA | Tang, Li,et al."Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC-DAD-ESI-MS/MS".JOURNAL OF NATURAL MEDICINES 64.2(2010):182-186. |
入库方式： OAI收割
来源：昆明植物研究所
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