中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells

文献类型:期刊论文

作者Zhao, Zhensheng1; Cao, Lixia1; Zhang, Tao1; Hu, Rui1; Wang, Shuangqing1; Li, Shayu1; Li, Yi2; Yang, Guoqiang1
刊名CHEMISTRYSELECT
出版日期2016-07-16
卷号1期号:11页码:2581-2585
关键词Fluorescence Probes Hydrogen Sulfide Tetrazine Group Bodipy 3t3 Fibroblast Cells
英文摘要Hydrogen Sulfide (H2S), a kind of important gas signal molecules, serves as an important medium in physiological and pathological studies. It is also a hot spot in the research of chemistry and biology. We now report a new type of reactionbased fluorescent probe for selective detecting H2S in living cells that adopts H2S reaction with tetrazine group (Tz) to dihydio-tetrazine. The fluorescence probes, BODIPY-Tz-I and BODIPY-Tz-II (BODIPY: abbreviation for boron-dipyrromethene), respond to H2S by a turn-on fluorescence signal enhancement and show high selectivity of H2S over other biologically species. BODIPY-Tz-I and BODIPY-Tz-II can be used to detect H2S in both buffer solution and cells in vivo, which provide a novel and effective approach for H2S detection in biological systems.
语种英语
源URL[http://ir.iccas.ac.cn/handle/121111/37930]  
专题化学研究所_高分子物理与化学实验室
作者单位1.Univ Chinese Acad Sci, Chinese Acad Sci, Inst Chem,Beijing Natl Lab Mol Sci, Key Lab Photochem, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Zhensheng,Cao, Lixia,Zhang, Tao,et al. Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells[J]. CHEMISTRYSELECT,2016,1(11):2581-2585.
APA Zhao, Zhensheng.,Cao, Lixia.,Zhang, Tao.,Hu, Rui.,Wang, Shuangqing.,...&Yang, Guoqiang.(2016).Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells.CHEMISTRYSELECT,1(11),2581-2585.
MLA Zhao, Zhensheng,et al."Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells".CHEMISTRYSELECT 1.11(2016):2581-2585.

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来源:化学研究所

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