Synthesis of formamides containing unsaturated groups by N-formylation of amines using CO2 with H-2
文献类型：期刊论文
| 作者 | Liu, Hangyu1,2; Mei, Qingqing1,2; Xu, Qingling2; Song, Jinliang1; Liu, Huizhen1,2; Han, Buxing1,2 |
| 刊名 | GREEN CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 19期号:1页码:196-201 |
| 英文摘要 | Formamides have wide applications in the industry and have been synthesized using CO2 as a carbon source and H-2 as a reducing agent. However, previous systems required a noble catalyst and high temperature to achieve high efficiency, and the substrate scope was mostly limited to saturated amines. The selective N-formylation of amines containing unsaturated groups using CO2 and H-2 is challenging because the efficient catalysts for the N-formylation are usually very active for hydrogenation of the unsaturated groups. Herein, we achieved for the first time a selective and efficient N-formylation of amines containing unsaturated groups using CO2 and H-2 with a Cu(OAc)(2)-4-dimethylaminopyridine (DMAP) catalytic system. The substrates were converted to the desired formamides, while the unsaturated groups, such as the carbonyl group, the C=C bond, C N bond and the ester group remained. The main reason for the excellent selectivity of the Cu(OAc)(2)-DMAP catalytic system was that it was very active for the N-formylation reaction, but was not active for the hydrogenation of the unsaturated groups. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/38016]  |
| 专题 | 化学研究所_胶体、界面与化学热力学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Colloid & Interface & Thermodynam, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Hangyu,Mei, Qingqing,Xu, Qingling,et al. Synthesis of formamides containing unsaturated groups by N-formylation of amines using CO2 with H-2[J]. GREEN CHEMISTRY,2017,19(1):196-201. |
| APA | Liu, Hangyu,Mei, Qingqing,Xu, Qingling,Song, Jinliang,Liu, Huizhen,&Han, Buxing.(2017).Synthesis of formamides containing unsaturated groups by N-formylation of amines using CO2 with H-2.GREEN CHEMISTRY,19(1),196-201. |
| MLA | Liu, Hangyu,et al."Synthesis of formamides containing unsaturated groups by N-formylation of amines using CO2 with H-2".GREEN CHEMISTRY 19.1(2017):196-201. |
入库方式： OAI收割
来源：化学研究所
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