Dually emissive P,N-co-doped carbon dots for fluorescent and photoacoustic tissue imaging in living mice
文献类型：期刊论文
| 作者 | Parvin, Nargish1,3; Mandal, Tapas K.2,3 |
| 刊名 | MICROCHIMICA ACTA
 |
| 出版日期 | 2017-04-01 |
| 卷号 | 184期号:4页码:1117-1125 |
| 关键词 | Carbon Quantumdots Dual Emission Quantum Yield Wavelength-dependent Emission Toxicity Mouse Tumor Cancer Diagnosis |
| 英文摘要 | Hydrothermal treatment of a mixture of ethylene diamine, phosphoric acid and citric acid under ambient pressure generates fluorescent carbon dots that are co-doped with phosphorus and nitrogen. These have features such as (a) both green fluorescence (peaking at 430 nm; 30% quantum yield) and red fluorescence (peaking at 500 nm, quantum yield 78%), (b) wavelength-dependent emission peaks, and (c) insensitivity to changes of pH values, dot concentration and ionic strength. The C-dots are useful for both fluorescent (FL) and photoacoustic (PA) imaging of living tissue. PA imaging warrants better spatial resolution and allows deeper tissues to be imaged compared to most optical imaging techniques. It is essential to assign a photoacoustic contrast agent as most of the diseases do not show a natural photoacoustic contrast in their early stage. The dually emitting C-dots are shown to be a useful contrast agent for PA and FL imaging of mice tumors. Intravenous administration of the C-dots resulted in strong signals in both PA and FL imaging. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/38082]  |
| 专题 | 化学研究所_活体分析化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Key Lab Biochem Engn, 1 Bei Erjie, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, Bei Yi Jie 2, Beijing 100190, Peoples R China 3.Indian Inst Technol, Dept Biotechnol, Roorkee 247667, Uttarakhand, India |
| 推荐引用方式 GB/T 7714 | Parvin, Nargish,Mandal, Tapas K.. Dually emissive P,N-co-doped carbon dots for fluorescent and photoacoustic tissue imaging in living mice[J]. MICROCHIMICA ACTA,2017,184(4):1117-1125. |
| APA | Parvin, Nargish,&Mandal, Tapas K..(2017).Dually emissive P,N-co-doped carbon dots for fluorescent and photoacoustic tissue imaging in living mice.MICROCHIMICA ACTA,184(4),1117-1125. |
| MLA | Parvin, Nargish,et al."Dually emissive P,N-co-doped carbon dots for fluorescent and photoacoustic tissue imaging in living mice".MICROCHIMICA ACTA 184.4(2017):1117-1125. |
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来源：化学研究所
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