Covalent tethering of photo-responsive superficial layers on hydrogel surfaces for photo-controlled release
文献类型：期刊论文
| 作者 | Chen, Lie1; Yao, Xi2; Gu, Zhandong1; Zheng, Kaikai3; Zhao, Chuangqi1; Lei, Wenwei1; Rong, Qinfeng1; Lin, Ling7; Wang, Jiaobing4; Jiang, Lei5 |
| 刊名 | CHEMICAL SCIENCE
 |
| 出版日期 | 2017 |
| 卷号 | 8期号:3页码:2010-2016 |
| 英文摘要 | The diffusion and transport of substances between a hydrogel and its environment have received tremendous research interest, due to the wide range of applications of hydrogel materials in fields related to drug carriers and drug delivery vehicles. To date, much research has been done to tailor the diffusion and transport of substances through hydrogels, where most efforts were focused on tuning the 3D network properties of the hydrogel including loop size, hydrophobicity of building blocks and the stimuli-responsive properties of backbones. These conventional strategies, however, usually suffer from complicated fabrication procedures and result in a homogeneous increase in hydrophobicity of the hydrogel network, leading to low efficiency control over the diffusion of substances through the hydrogel. Herein, a facile strategy that can functionalize the surfaces of hydrogels, while keeping the interior network unchanged, was reported, and is realized by quaternization reaction confined to the hydrogel/oil interface. Owing to the introduction of the photo-responsive molecule IBSP as a modifier, the surface wettability of the resulting hydrogel can be controlled by light both in air and underwater environments. Consequently, the diffusion rate of a substance through this modified hydrogel can be regulated by light, which brings convenience to the controlled release of hydrogels and other hydrogelrelated fields. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/38161]  |
| 专题 | 化学研究所_胶体、界面与化学热力学实验室 |
| 作者单位 | 1.Beihang Univ, Key Lab Bioinspired Smart Interfacial Sci & Techn, Minist Educ, Sch Chem & Environm, Beijing 100191, Peoples R China 2.Harvard Univ, Kavli Inst Nanobio Sci & Technol, Sch Engn & Appl Sci, Cambridge, MA 02138 USA 3.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 4.Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China 5.Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Bioinspired Mat & Interfacial Sci, Beijing 100190, Peoples R China 6.Beihang Univ, Int Res Inst Multidisciplinary Sci, Beijing 100191, Peoples R China 7.State Ocean Adm, Inst Oceanog 3, SOA, Engn Res Ctr Marine Biol Resource Comprehens Util, Xiamen 361005, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Lie,Yao, Xi,Gu, Zhandong,et al. Covalent tethering of photo-responsive superficial layers on hydrogel surfaces for photo-controlled release[J]. CHEMICAL SCIENCE,2017,8(3):2010-2016. |
| APA | Chen, Lie.,Yao, Xi.,Gu, Zhandong.,Zheng, Kaikai.,Zhao, Chuangqi.,...&Liu, Mingjie.(2017).Covalent tethering of photo-responsive superficial layers on hydrogel surfaces for photo-controlled release.CHEMICAL SCIENCE,8(3),2010-2016. |
| MLA | Chen, Lie,et al."Covalent tethering of photo-responsive superficial layers on hydrogel surfaces for photo-controlled release".CHEMICAL SCIENCE 8.3(2017):2010-2016. |
入库方式： OAI收割
来源：化学研究所
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