Near-infrared (NIR) controlled reversible cell adhesion on a responsive nano-biointerface
文献类型：期刊论文
| 作者 | Cui, Haijun1,2; Zhang, Pengchao2,3; Wang, Wenshuo1,2; Li, Guannan2,3; Hao, Yuwei2,3; Wang, Luying2,3; Wang, Shutao1,2 |
| 刊名 | NANO RESEARCH
 |
| 出版日期 | 2017-04-01 |
| 卷号 | 10期号:4页码:1345-1355 |
| 关键词 | Cell Adhesion Photothermal Effect Nanostructures Bio-interface Hydrophobic Interaction |
| 英文摘要 | Light-activated dynamic variations have promoted the development of smart interfaces, especially nano-biointerfaces. In this article, the near-infrared (NIR)responsive surface for controlling cell adhesion was designed by grafting a thermal responsive polymer (poly(N-isopropylacrylamide), PNIPAM) onto silicon nanowires (SiNWs) instead of the traditional photosensitive moieties. NIR induced the photothermal effect of the SiNWs, and the local heat induced thermodynamic phase transformation of PNIPAM. With the application of NIR radiation, the surface turned to a hydrophobic state, and restored to the hydrophilic state when NIR was switched off, leading to reversible cell adhesion and release. The switchable wettability of the surface and cell adhesion/release occurred efficiently even after 20 cycles. Proteins were anchored on the surface via hydrophobic interactions using NIR; further connection of a cell-capture agent helped in achieving specific cell capture. This dynamic control of cell adhesion via NIR may provide new clues for designing functional nano-biointerfaces. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/38239]  |
| 专题 | 化学研究所_有机固体实验室 |
| 作者单位 | 1.Chinese Acad Sci, CAS Key Lab Bioinspired Mat & Interfacial Sci, CAS Ctr Excellence Nanosci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cui, Haijun,Zhang, Pengchao,Wang, Wenshuo,et al. Near-infrared (NIR) controlled reversible cell adhesion on a responsive nano-biointerface[J]. NANO RESEARCH,2017,10(4):1345-1355. |
| APA | Cui, Haijun.,Zhang, Pengchao.,Wang, Wenshuo.,Li, Guannan.,Hao, Yuwei.,...&Wang, Shutao.(2017).Near-infrared (NIR) controlled reversible cell adhesion on a responsive nano-biointerface.NANO RESEARCH,10(4),1345-1355. |
| MLA | Cui, Haijun,et al."Near-infrared (NIR) controlled reversible cell adhesion on a responsive nano-biointerface".NANO RESEARCH 10.4(2017):1345-1355. |
入库方式： OAI收割
来源：化学研究所
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