Biofilm Inhibition and Elimination Regulated by Cationic Conjugated Polymers
文献类型：期刊论文
| 作者 | Zhang, Pengbo; Li, Shengliang; Chen, Hui; Wang, Xiaoyu; Liu, Libing; Lv, Fengting; Wang, Shu |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2017-05-24 |
| 卷号 | 9期号:20页码:16934-16939 |
| 关键词 | Conjugated Polymer Biofilm Inhibition Elimination Ros |
| 英文摘要 | In this work, we demonstrate that water-soluble conjugated polymers (PFP) have the ability to inhibit biofilm formation and eradicate mature established biofilm using reactive oxygen species (ROS) produced by PFP under white light irradiation. Upon addition of PFP to planktonic Staphylococcus aureus (S. aureus), electrostatic interactions bring cationic PFP to the surface of S. aureus, which possesses negative charges. As the amount of PFP coated on S. aureus becomes saturated, the interactions of bacteria to bacteria and bacteria to surface may be disrupted, resulting in reduced biofilm formation. After the biofilm matures, those PFP on the surface of the biofilm can generate ROS under white light irradiation, which has the ability to inactivate bacteria nearby. Once the biofilm is broken, PFP can penetrate throughthe biofilm and continuously generate ROS under irradiation, resulting in biofilm disruption. As a consequence, this makes conjugated polymers a very promising material for the disruption of biofilm in biomedical and industrial applications. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/38492]  |
| 专题 | 化学研究所_有机固体实验室 |
| 作者单位 | Chinese Acad Sci, Nstitute Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Pengbo,Li, Shengliang,Chen, Hui,et al. Biofilm Inhibition and Elimination Regulated by Cationic Conjugated Polymers[J]. ACS APPLIED MATERIALS & INTERFACES,2017,9(20):16934-16939. |
| APA | Zhang, Pengbo.,Li, Shengliang.,Chen, Hui.,Wang, Xiaoyu.,Liu, Libing.,...&Wang, Shu.(2017).Biofilm Inhibition and Elimination Regulated by Cationic Conjugated Polymers.ACS APPLIED MATERIALS & INTERFACES,9(20),16934-16939. |
| MLA | Zhang, Pengbo,et al."Biofilm Inhibition and Elimination Regulated by Cationic Conjugated Polymers".ACS APPLIED MATERIALS & INTERFACES 9.20(2017):16934-16939. |
入库方式： OAI收割
来源：化学研究所
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