Cytosine-Cytosine Base-Pair Mismatch and Chirality in Nucleotide Supramolecular Coordination Complexes
文献类型：期刊论文
| 作者 | Qiu, Qi-Ming1; Zhou, Pei1; Gu, Leilei1; Hao, Liang1; Liu, Minghua2; Li, Hui1 |
| 刊名 | CHEMISTRY-A EUROPEAN JOURNAL
 |
| 出版日期 | 2017-05-29 |
| 卷号 | 23期号:30页码:7201-7206 |
| 关键词 | Base-pair Mismatch Chirality Crystal Structures I-motif Nucleotide |
| 英文摘要 | The base-pair sequences are the foundation for the biological processes of DNA or RNA, and base-pair mismatch is very important to reveal genetic diseases and DNA rearrangements. However, the lack of well-defined structural information about base-pair mismatch is obstructing the investigation of this issue. The challenge is to crystallize the materials containing the base-pair mismatch. Engineering the small-molecule mimics or model is an effective strategy to solve this issue. Here, six cytidine5'-monophosphate (CMP) and 2'-deoxycytidine-5'-monophosphate (dCMP) coordination polymers were reported containing cytosine-cytosine base-pair mismatch (i-motif), and their single-crystal structures and chiralities were studied. The precise control over the formation of the i-motif was demonstrated, in which the regulating of supramolecular interactions was achieved based on molecular design. In addition, the chiralities of these coordination polymers were investigated according to their crystal structures and solution- and solid-state circular dichroism spectroscopy. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/38535]  |
| 专题 | 化学研究所_胶体、界面与化学热力学实验室 |
| 作者单位 | 1.Beijing Inst Technol, Sch Chem & Chem Engn, Minist Educ, Key Lab Cluster Sci, Beijing 100081, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiu, Qi-Ming,Zhou, Pei,Gu, Leilei,et al. Cytosine-Cytosine Base-Pair Mismatch and Chirality in Nucleotide Supramolecular Coordination Complexes[J]. CHEMISTRY-A EUROPEAN JOURNAL,2017,23(30):7201-7206. |
| APA | Qiu, Qi-Ming,Zhou, Pei,Gu, Leilei,Hao, Liang,Liu, Minghua,&Li, Hui.(2017).Cytosine-Cytosine Base-Pair Mismatch and Chirality in Nucleotide Supramolecular Coordination Complexes.CHEMISTRY-A EUROPEAN JOURNAL,23(30),7201-7206. |
| MLA | Qiu, Qi-Ming,et al."Cytosine-Cytosine Base-Pair Mismatch and Chirality in Nucleotide Supramolecular Coordination Complexes".CHEMISTRY-A EUROPEAN JOURNAL 23.30(2017):7201-7206. |
入库方式： OAI收割
来源：化学研究所
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