Interactions of Phospholipid Vesicles with Cationic and Anionic Oligomeric Surfactants
文献类型：期刊论文
| 作者 | Chen, Yao1,2; Qiao, Fulin1,2; Fan, Yaxun1; Han, Yuchun1; Wang, Yilin1,2 |
| 刊名 | JOURNAL OF PHYSICAL CHEMISTRY B
 |
| 出版日期 | 2017-07-27 |
| 卷号 | 121期号:29页码:7122-7132 |
| 英文摘要 | This work studied the interactions of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) with cationic ammonium surfactants and anionic sulfate or sulfonate surfactants of different oligomeric degrees, including cationic monomeric DTAB, dimeric C12C3C12Br2, and trimeric DDAD as well as anionic monomeric SDS, dimeric C12C3C12(SO3)(2), and trimeric TED-(C10SO3Na)(3). The partition coefficient P of these surfactants between the DOPC vesicles and water was determined with isothermal titration microcalorimetry (ITC) by titrating concentrated DOPC solution into the monomer solution of these surfactants. It was found that the P value increases with the increase of the surfactant oligomeric degree. Moreover, the enthalpy change and the Gibbs free energy for the transition of these surfactants from water into the DOPC bilayer become more negative with increasing the oligomeric degree. Meanwhile, the calcein release experiment proves that the surfactant with a higher oligomeric degree shows stronger ability of changing the permeability of the DOPC vesicles. Furthermore, the solubilization of the DOPC vesicles by these oligomeric surfactants was studied by ITC, turbidity, and dynamic light scattering, and thus the phase boundaries for the surfactant/lipid mixtures have been determined. The critical surfactant to lipid ratios for the onset and end of the solubilization for the DOPC vesicles derived from the phase boundaries decrease remarkably with increasing the oligomeric degree. Overall, the surfactant with a larger oligomerization degree shows stronger ability in incorporating into the lipid bilayer, altering the membrane permeability and solubilizing lipid vesicles, which provides comprehensive understanding about the effects of structure and shape of oligomeric surfactant molecules on lipid-surfactant interactions. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/39215]  |
| 专题 | 化学研究所_胶体、界面与化学热力学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Colloid & Interface Sci, Beijing Natl Lab Mol Sci, CAS Res Educ Ctr Excellence Mol Sci,Inst Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yao,Qiao, Fulin,Fan, Yaxun,et al. Interactions of Phospholipid Vesicles with Cationic and Anionic Oligomeric Surfactants[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2017,121(29):7122-7132. |
| APA | Chen, Yao,Qiao, Fulin,Fan, Yaxun,Han, Yuchun,&Wang, Yilin.(2017).Interactions of Phospholipid Vesicles with Cationic and Anionic Oligomeric Surfactants.JOURNAL OF PHYSICAL CHEMISTRY B,121(29),7122-7132. |
| MLA | Chen, Yao,et al."Interactions of Phospholipid Vesicles with Cationic and Anionic Oligomeric Surfactants".JOURNAL OF PHYSICAL CHEMISTRY B 121.29(2017):7122-7132. |
入库方式： OAI收割
来源：化学研究所
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