A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH
文献类型：期刊论文
| 作者 | Jiang, Guoyu1; Liu, Xiang1; Chen, Qingqing1; Zeng, Guanjie1; Wu, Yongquan1; Dong, Xiaobiao2; Zhang, Guanxin2; Li, Yongdong1; Fan, Xiaolin1; Wang, Jianguo1 |
| 刊名 | SENSORS AND ACTUATORS B-CHEMICAL
 |
| 出版日期 | 2017-11-01 |
| 卷号 | 252页码:712-716 |
| 关键词 | Fluorescence Turn-on Sensor Aggregation Induced Emission Discriminatory Detection Of Cys Tetraphenylethylene Derivatives |
| 英文摘要 | A tetraphenylethylene based aggregation induced emission (AIE) probe, TPENNO2, bearing a 2,4-dinitrobenzenesulfonyl pendant was designed and synthesized for light-up and discriminatory detection of Cys over Hcy and GSH in PBS. The 2,4-dinitrobenzenesulfonyl group quenched the fluorescence of TPENNO2. While after thiol group promoted nucleophilic aromatic substitution reaction, TPENNO2 can be converted to fluorescent TPENH2. The discriminatory detection of Cys over Hcy and GSH comes from the different reaction kinetic profiles of TPENNO2 with the thiol residues of Cys, Hcy and GSH. Moreover, TPENNO2 can be used to image biothiols in living HeLa cells. (C) 2017 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/39332]  |
| 专题 | 化学研究所_有机固体实验室 |
| 作者单位 | 1.Gannan Normal Univ, Key Lab Organopharmaceut Chem, Ganzhou 341000, Peoples R China 2.Chinese Acad Sci, Inst Chem, Organ Solids Lab, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Guoyu,Liu, Xiang,Chen, Qingqing,et al. A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH[J]. SENSORS AND ACTUATORS B-CHEMICAL,2017,252:712-716. |
| APA | Jiang, Guoyu.,Liu, Xiang.,Chen, Qingqing.,Zeng, Guanjie.,Wu, Yongquan.,...&Wang, Jianguo.(2017).A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH.SENSORS AND ACTUATORS B-CHEMICAL,252,712-716. |
| MLA | Jiang, Guoyu,et al."A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH".SENSORS AND ACTUATORS B-CHEMICAL 252(2017):712-716. |
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来源：化学研究所
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