Light-Responsive Janus-Particle-Based Coatings for Cell Capture and Release
文献类型：期刊论文
| 作者 | Cao, Ziquan1,2; Bian, Qing1; Chen, Ying2; Liang, Fuxin2; Wang, Guojie1 |
| 刊名 | ACS MACRO LETTERS
 |
| 出版日期 | 2017-10-01 |
| 卷号 | 6期号:10页码:1124-1128 |
| 英文摘要 | A robust light-responsive coating based on Janus composite particles is achieved. First, strawberry-like silica Janus particles are synthesized by the sol-gel process at a patchy emulsion interface. One side of the silica Janus particles possesses nanoscale roughness, and the other side is flat. Then, spiropyran-containing polymer brushes are grafted onto the coarse hemispherical side of the as-synthesized Janus particles, and the other flat side is modified with imidazoline groups. The light-responsive polymer brush-terminated coarse hemispherical sides direct toward the air when the Janus composite particles self-organize into a layer on the surface of epoxy resin substrate. The imidazoline groups react with the epoxy groups in the epoxy resin to form a robust smart coating. The coating can be reversibly triggered between hydrophobic and hydrophilic by UV and visible-light irradiation, which is attributed to the isomerization of spiropyran moieties. When the hydrophobic ring-closed spiropyran form is prominent, HeLa cells can be effectively captured onto the coating. After UV light irradiation, the ring-closed spiropyran form changes to the hydrophilic ring-opened zwitterionic merocyanine form, and then the captured cells are released. This work shows promising potential for engineering advanced smart biointerfaces. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/41299]  |
| 专题 | 化学研究所_高分子物理与化学实验室 |
| 作者单位 | 1.Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Ziquan,Bian, Qing,Chen, Ying,et al. Light-Responsive Janus-Particle-Based Coatings for Cell Capture and Release[J]. ACS MACRO LETTERS,2017,6(10):1124-1128. |
| APA | Cao, Ziquan,Bian, Qing,Chen, Ying,Liang, Fuxin,&Wang, Guojie.(2017).Light-Responsive Janus-Particle-Based Coatings for Cell Capture and Release.ACS MACRO LETTERS,6(10),1124-1128. |
| MLA | Cao, Ziquan,et al."Light-Responsive Janus-Particle-Based Coatings for Cell Capture and Release".ACS MACRO LETTERS 6.10(2017):1124-1128. |
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来源：化学研究所
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