Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection
文献类型：期刊论文
| 作者 | Liu, Xiaomeng2; Xiao, Tongfang1; Wu, Fei1; Shen, Mo-Yuan3; Zhang, Meining2; Yu, Hsiao-hua3; Mao, Lanqun1 |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2017-09-18 |
| 卷号 | 56期号:39页码:11802-11806 |
| 关键词 | Antifouling Dopamine Electropolymerization Invivo Studies Phosphocholine |
| 英文摘要 | Resisting biomolecule adsorption onto the surface of brain-implanted microelectrodes is a key issue for invivo monitoring of neurochemicals. Herein, we demonstrate that an ultrathin cell-membrane-mimic film of ethylenedioxythiophene tailored with zwitterionic phosphorylcholine (EDOT-PC) electropolymerized onto the surface of a carbon fiber microelectrode (CFE) not only resists protein adsorption but also maintains the sensitivity and time response for invivo monitoring of dopamine (DA). As a consequence, the as-prepared PEDOT-PC/CFEs could be used as a new reliable platform for tracking DA invivo and would help understand the physiological and pathological functions of DA. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/41063]  |
| 专题 | 化学研究所_活体分析化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Inst Chem, Beijing 100190, Peoples R China 2.Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China 3.Acad Sinica, Inst Chem, 128 Acad Rd,Sec 2, Taipei 11529, Taiwan |
| 推荐引用方式 GB/T 7714 | Liu, Xiaomeng,Xiao, Tongfang,Wu, Fei,et al. Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2017,56(39):11802-11806. |
| APA | Liu, Xiaomeng.,Xiao, Tongfang.,Wu, Fei.,Shen, Mo-Yuan.,Zhang, Meining.,...&Mao, Lanqun.(2017).Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,56(39),11802-11806. |
| MLA | Liu, Xiaomeng,et al."Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 56.39(2017):11802-11806. |
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来源：化学研究所
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