New chiral ligand exchange capillary electrophoresis system with chiral amino amide ionic liquids as ligands
文献类型：期刊论文
| 作者 | Jiang, Junfang1,2; Mu, Xiaoyu3; Qiao, Juan1,2; Su, Yuan1,4; Qi, Li1,2 |
| 刊名 | TALANTA
 |
| 出版日期 | 2017-12-01 |
| 卷号 | 175页码:451-456 |
| 关键词 | Amino Amide Ionic Liquids Chiral Ligand Exchange Capillary Electrophoresis Enantioseparation Of d L-amino Acids |
| 英文摘要 | Using chiral amino amide ionic liquids as the ligands, a new chiral ligand exchange capillary electrophoresis method with Cu(II) as the central ion was constructed for enantioseparation of labeled D,L-amino acids. The effects of key parameters, including pH value of the running buffer, the ratio of Cu(II) to chiral amino amide ionic liquids, the concentration of complexes based on Cu(II)-chiral amino amide ionic liquids were investigated. It has been observed that eight pairs of labeled D,L-amino acids could be baseline-separated with a running buffer of 15.0 mM ammonium acetate, 10.0 mM Cu(II) and 20.0 mM L-phenylalaninamide based ionic liquid at pH 5.0. The quantitation of D,L-amino acids was conducted and good linearity (r(2) >= 0.964) was obtained. Furthermore, an assay for determining the enantiomeric purity of D,L-amino acids was developed and the possible enantiorecognition mechanism was discussed briefly. The results indicated that the chiral amino amide ionic liquids could play the role of ligands in chiral ligand exchange capillary electrophoresis system and exhibit great potential in chiral analysis. |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/41248]  |
| 专题 | 化学研究所_活体分析化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, 2 Zhongguancun Beiyijie, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, 19A Yuquanlu, Beijing 100049, Peoples R China 3.Chengdu Univ Tradit Chinese Med, Chengdu 611137, Sichuan, Peoples R China 4.Shandong Agr Univ, Tai An 271018, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Junfang,Mu, Xiaoyu,Qiao, Juan,et al. New chiral ligand exchange capillary electrophoresis system with chiral amino amide ionic liquids as ligands[J]. TALANTA,2017,175:451-456. |
| APA | Jiang, Junfang,Mu, Xiaoyu,Qiao, Juan,Su, Yuan,&Qi, Li.(2017).New chiral ligand exchange capillary electrophoresis system with chiral amino amide ionic liquids as ligands.TALANTA,175,451-456. |
| MLA | Jiang, Junfang,et al."New chiral ligand exchange capillary electrophoresis system with chiral amino amide ionic liquids as ligands".TALANTA 175(2017):451-456. |
入库方式： OAI收割
来源：化学研究所
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