Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels
文献类型：期刊论文
| 作者 | Wang, JB; Chao, J; Liu, HJ; Su, S; Wang, LH; Huang, W; Willner, I; Fan, CH |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2017 |
| 卷号 | 56期号:8页码:2171-2175 |
| 关键词 | Dna Hydrogels Dna Nanotechnology Nucleic Acid Hybridization Self-assembly Sol-gel Process |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201610125 |
| 文献子类 | 期刊论文 |
| 英文摘要 | DNA hydrogels hold great potential for biological and biomedical applications owing to their programmable nature and macroscopic sizes. However, most previous studies involve spontaneous and homogenous gelation procedures in solution, which often lack precise control. A clamped hybridization chain reaction (C-HCR)-based strategy has been developed to guide DNA self-assembly to form macroscopic hydrogels. Analogous to catalysts in chemical synthesis or seeds in crystal growth, we introduced DNA initiators to induce the gelation process, including crosslinked self-assembly and clamped hybridization in three dimensions with spatial and temporal control. The formed hydrogels show superior mechanical properties. The use of printed, surface-confined DNA initiators was also demonstrated for fabricating 2D hydrogel patterns without relying on external confinements. This simple method can be used to construct DNA hydrogels with defined geometry, composition, and order for various bioapplications. |
| 语种 | 英语 |
| WOS记录号 | WOS:000397323300038 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/27274]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Wang, JB,Chao, J,Liu, HJ,et al. Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2017,56(8):2171-2175. |
| APA | Wang, JB.,Chao, J.,Liu, HJ.,Su, S.,Wang, LH.,...&Fan, CH.(2017).Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,56(8),2171-2175. |
| MLA | Wang, JB,et al."Clamped Hybridization Chain Reactions for the Self-Assembly of Patterned DNA Hydrogels".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 56.8(2017):2171-2175. |
入库方式： OAI收割
来源：上海应用物理研究所
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