Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection
文献类型：期刊论文
| 作者 | Su, J; Wang, DF; Norbel, L; Shen, JL; Zhao, ZH; Dou, YZ; Peng, TH; Shi, JY; Mathur, S; Fan, CH |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 89期号:4页码:2531-2538 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/acs.analchem.6b04729 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Uniform silver-containing metal nanostructures with strong and stable surface enhanced Raman scattering (SERS) signals hold great promise for developing ultrasensitive probes for biodetection. Nevertheless, the direct synthesis of such ready-to-use nanoprobes remains extremely challenging. Herein we report a DNA-mediated gold silver nanomushroom with interior nanogaps directly synthesized and used for multiplex and simultaneous SERS detection of various DNA and RNA targets. The DNA involved in the nanostructures can act as hot only gap DNA (mediated DNA) but also probe DNA (hybridized DNA), and DNA's involvement enables the nanostructures to have the inherent ability to recognize DNA and RNA targets. Importantly, we were the first to establish a new method for the generation of multicolor SERS probes using two different strategies. First Raman-labeled alkanethiol probe DNA was assembled on gold nanoparticles, and second, thiol-containing Raman reporters were coassembled with the probe DNA. The ready-to-use probes also give great potential to develop ultrasensitive detection methods for various biological molecules. |
| 语种 | 英语 |
| WOS记录号 | WOS:000394724700050 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/27389]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Su, J,Wang, DF,Norbel, L,et al. Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection[J]. ANALYTICAL CHEMISTRY,2017,89(4):2531-2538. |
| APA | Su, J.,Wang, DF.,Norbel, L.,Shen, JL.,Zhao, ZH.,...&Song, SP.(2017).Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection.ANALYTICAL CHEMISTRY,89(4),2531-2538. |
| MLA | Su, J,et al."Multicolor Gold Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection".ANALYTICAL CHEMISTRY 89.4(2017):2531-2538. |
入库方式： OAI收割
来源：上海应用物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。