Recognizing single phospholipid vesicle collisions on carbon fiber nanoelectrode
文献类型：期刊论文
| 作者 | Zhang, YY; Li, M; Li, ZH; Li, Q; Aldalbahi, A; Shi, JY; Wang, LH; Fan, CH; Zuo, XL |
| 刊名 | SCIENCE CHINA-CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 60期号:11页码:1474-1480 |
| 关键词 | Electrochemical Detection Dna-nanostructure Dopamine Release Cells Amperometry Exocytosis Events Ultramicroelectrode Microelectrodes Transmitters |
| ISSN号 | 1674-7291 |
| DOI | 10.1007/s11426-017-9036-0 |
| 文献子类 | 期刊论文 |
| 英文摘要 | We recognize the stochastic collisions of dopamine contained phospholipid vesicle on carbon fiber nanoelectrode, extending the observation of discrete collision events on nanoelectrode to biologically relevant analytes. To decrease noise interference to the technique, the dimensions of nanoelectrode was systematically investigated and optimized. Scanning electron microscopy (SEM) further supported the comparable sizes of nanoelectrode and vesicles (similar to 100 nm in diameter). Vesicles collision and rupture on the surface of nanoelectrode led to the dopamine release from vesicles, which could be electrochemically oxidized to dopamine-o-quinone and detected via voltammetry. The comparable size of the nanoelectrode with vesicles and fast voltammetry allowed differentiation of single collision events from the current magnitudes and peak widths in the electrochemical collision experiments, which shows the efficacy of the method to characterize vesicle samples. This work provides a foundation upon which quantitative sensor technology might be built for the detection of dopamine contained vesicles with high spatial and temporal resolution. |
| WOS关键词 | ELECTROCHEMICAL DETECTION ; DNA-NANOSTRUCTURE ; DOPAMINE RELEASE ; CELLS ; AMPEROMETRY ; EXOCYTOSIS ; EVENTS ; ULTRAMICROELECTRODE ; MICROELECTRODES ; TRANSMITTERS |
| 语种 | 英语 |
| WOS记录号 | WOS:000414378700014 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/28798]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Zhang, YY,Li, M,Li, ZH,et al. Recognizing single phospholipid vesicle collisions on carbon fiber nanoelectrode[J]. SCIENCE CHINA-CHEMISTRY,2017,60(11):1474-1480. |
| APA | Zhang, YY.,Li, M.,Li, ZH.,Li, Q.,Aldalbahi, A.,...&Zuo, XL.(2017).Recognizing single phospholipid vesicle collisions on carbon fiber nanoelectrode.SCIENCE CHINA-CHEMISTRY,60(11),1474-1480. |
| MLA | Zhang, YY,et al."Recognizing single phospholipid vesicle collisions on carbon fiber nanoelectrode".SCIENCE CHINA-CHEMISTRY 60.11(2017):1474-1480. |
入库方式： OAI收割
来源：上海应用物理研究所
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