Ferumoxytol of ultrahigh magnetization produced by hydrocooling and magnetically internal heating co-precipitation
文献类型：期刊论文
| 作者 | Chen, B; Sun, JF; Fan, FG; Zhang, XZ; Qin, ZG; Wang, P; Li, Y; Zhang, XQ; Liu, F; Liu, YL |
| 刊名 | NANOSCALE
 |
| 出版日期 | 2018 |
| 卷号 | 10期号:16页码:7369-7376 |
| 关键词 | Iron-oxide Nanoparticles Electron-paramagnetic-resonance Mri Contrast Agents Field Control Nanomaterials Nanostructures Temperature Particles Design |
| ISSN号 | 2040-3364 |
| DOI | 10.1039/c8nr00736e |
| 文献子类 | 期刊论文 |
| 英文摘要 | Ferumoxytol, which is originally intended for MRI and anemia treatment, is currently the only inorganic nanodrug approved by FDA for clinical application in vivo. Common ferumoxytol seems incapable of meeting the requirements for diverse applications. Thus, the development of a novel strategy based on co-precipitation to produce ferumoxytol with high quality is an imminent task. Herein, we proposed a physically assisted strategy, namely hydrocooling and magnetically internal heating co-precipitation, to optimize the properties of ferumoxytol and thus significantly enhance its magnetic performance. Magnetization of the newly developed ferumoxytol can reach 104-105 emu g(-1) Fe, which is the highest value among the reported results. It has been found that the crystalline structures of the newly developed ferumoxytol have been greatly improved on the basis of pharmaceutical quality criteria. |
| 语种 | 英语 |
| WOS记录号 | WOS:000431030000006 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/29020]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Chen, B 2.Sun, JF 3.Fan, FG 4.Zhang, XZ 5.Qin, ZG 6.Wang, P 7.Li, Y 8.Zhang, XQ 9.Liu, F 10.Liu, YL |
| 推荐引用方式 GB/T 7714 | Chen, B,Sun, JF,Fan, FG,et al. Ferumoxytol of ultrahigh magnetization produced by hydrocooling and magnetically internal heating co-precipitation[J]. NANOSCALE,2018,10(16):7369-7376. |
| APA | Chen, B.,Sun, JF.,Fan, FG.,Zhang, XZ.,Qin, ZG.,...&Gu, N.(2018).Ferumoxytol of ultrahigh magnetization produced by hydrocooling and magnetically internal heating co-precipitation.NANOSCALE,10(16),7369-7376. |
| MLA | Chen, B,et al."Ferumoxytol of ultrahigh magnetization produced by hydrocooling and magnetically internal heating co-precipitation".NANOSCALE 10.16(2018):7369-7376. |
入库方式： OAI收割
来源：上海应用物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。