Imaging of Colorectal Cancers Using Activatable Nanoprobes with Second Near-Infrared Window Emission
文献类型：期刊论文
| 作者 | Xu, G; Yan, QL; Lv, XG; Zhu, Y; Xin, K; Shi, B; Wang, RC; Chen, J; Gao, W; Shi, P |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2018 |
| 卷号 | 57期号:14页码:3626-3630 |
| 关键词 | In-vivo Fluorescence Hydrogen-sulfide Carbon Nanotubes Biological-systems Ii Fluorescence Probes Cells Mice Dye Nanoparticles |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201712528 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Fluorescent probes in the second near-infrared window (NIR-II) allow high-resolution bioimaging with deep-tissue penetration. However, existing NIR-II materials often have poor signal-to-background ratios because of the lack of target specificity. Herein, an activatable NIR-II nanoprobe for visualizing colorectal cancers was devised. This designed probe displays H2S-activated ratiometric fluorescence and light-up NIR-II emission at 900-1300nm. By using this activatable and target specific probe for deep-tissue imaging of H2S-rich colon cancer cells, accurate identification of colorectal tumors in animal models were performed. It is anticipated that the development of activatable NIR-II probes will find widespread applications in biological and clinical systems. |
| 语种 | 英语 |
| WOS记录号 | WOS:000428350100013 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/29038]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Xu, G 2.Yan, QL 3.Lv, XG 4.Zhu, Y 5.Xin, K 6.Shi, B 7.Wang, RC 8.Chen, J 9.Gao, W 10.Shi, P |
| 推荐引用方式 GB/T 7714 | Xu, G,Yan, QL,Lv, XG,et al. Imaging of Colorectal Cancers Using Activatable Nanoprobes with Second Near-Infrared Window Emission[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2018,57(14):3626-3630. |
| APA | Xu, G.,Yan, QL.,Lv, XG.,Zhu, Y.,Xin, K.,...&Tian, H.(2018).Imaging of Colorectal Cancers Using Activatable Nanoprobes with Second Near-Infrared Window Emission.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,57(14),3626-3630. |
| MLA | Xu, G,et al."Imaging of Colorectal Cancers Using Activatable Nanoprobes with Second Near-Infrared Window Emission".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 57.14(2018):3626-3630. |
入库方式： OAI收割
来源：上海应用物理研究所
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