Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric
文献类型：期刊论文
| 作者 | Li, R; Cai, XM; Ye, Y; Wu, GZ |
| 刊名 | JOURNAL OF APPLIED POLYMER SCIENCE
 |
| 出版日期 | 2018 |
| 卷号 | 135期号:9页码:- |
| 关键词 | Induced Graft-polymerization Anticoagulant Activity Blood Compatibility Styrene-sulfonate Heparin Chitosan Surface Biocompatibility Antibacterial Particles |
| ISSN号 | 0021-8995 |
| DOI | 10.1002/APP.45915 |
| 文献子类 | 期刊论文 |
| 英文摘要 | The sulfonated polypropylene non-woven fabric (PPNWF) was successfully fabricated via gamma-ray simultaneous radiationinduced graft polymerization of acrylic acid (AA)/sodium styrenesulfonate (NaSS) and acrylamide (AAm)/NaSS. The existence of graft chains in both PP-g-P(AA-co-NaSS) and PP-g-P(AAm-co-NaSS) was proved by attenuated total reflection Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. Water contact angle measurement illustrated the sulfonated PPNWF owning good hydrophilicity. The in vitro hemocompatibility evaluation showed that both PP-g-P(AA-co-NaSS) and PP-g-P(AAm-co-NaSS) inhibited effectively the adhesion of platelets and were significantly compatible with erythrocytes. Moreover, no obvious difference was confirmed in the prevention of platelet adhesion and hemolysis ratio between carboxyl and amide groups. However, as compared with that of PP-g-P(AAm-co-NaSS), PP-g-P(AA-co-NaSS) exhibited outstanding anticoagulant activity via increased activated partial thromboplastin time and thrombin time. This result indicated that the carboxyl group but not amide group featured strong synergistic effect on the anticoagulant activity of sulfonated PPNWF. (C) 2017 Wiley Periodicals, Inc. |
| 语种 | 英语 |
| WOS记录号 | WOS:000417600100019 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/29048]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 作者单位 | 1.Li, R 2.Cai, XM 3.Ye, Y 4.Wu, GZ |
| 推荐引用方式 GB/T 7714 | Li, R,Cai, XM,Ye, Y,et al. Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2018,135(9):-. |
| APA | Li, R,Cai, XM,Ye, Y,&Wu, GZ.(2018).Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric.JOURNAL OF APPLIED POLYMER SCIENCE,135(9),-. |
| MLA | Li, R,et al."Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non-woven fabric".JOURNAL OF APPLIED POLYMER SCIENCE 135.9(2018):-. |
入库方式： OAI收割
来源：上海应用物理研究所
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