A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood
文献类型：期刊论文
| 作者 | Li, X. K.; Y. L. Zhang; B. Xue; X. G. Kong; X. M. Liu; L. P. Tu; Y. L. Chang and H. Zhang |
| 刊名 | Biosensors & Bioelectronics
 |
| 出版日期 | 2017 |
| 卷号 | 92 |
| 英文摘要 | Assay technologies capable of detecting biomarker concentrations in unprocessed whole blood samples are fundamental for applications in medical diagnostics. SERS nano-tags integrated fiber-optic biosensor (FOB) was realized for the first time for in situ immunoassay in whole blood. The reliability and sensitivity of this method rely, in a large extent, on the quality and properties of the SERS nano-tags. The constructed silica coated Ag SERS nano-tags as labels were used in a rapid and specific in situ FOB immune sensor to detect alpha fetoprotein (AFP) in unprocessed blood samples. Preliminary results of in vivo and in situ dynamic observation of AFP of whole blood in wistar rat highlight the power of this new method. |
| 语种 | 英语 |
| 源URL | [http://ir.ciomp.ac.cn/handle/181722/59024]  |
| 专题 | 长春光学精密机械与物理研究所_中科院长春光机所知识产出 |
| 推荐引用方式 GB/T 7714 | Li, X. K.,Y. L. Zhang,B. Xue,et al. A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood[J]. Biosensors & Bioelectronics,2017,92. |
| APA | Li, X. K..,Y. L. Zhang.,B. Xue.,X. G. Kong.,X. M. Liu.,...&Y. L. Chang and H. Zhang.(2017).A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood.Biosensors & Bioelectronics,92. |
| MLA | Li, X. K.,et al."A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood".Biosensors & Bioelectronics 92(2017). |
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