Study on Mathematical Model and Simulation of Sandwich-type Lateral Flow Immunoassay.
文献类型：期刊论文
| 作者 | Zeng Nian-Yin; Zhu Pan-Pan; Li Yu-Rong; Jiang Hai-Yan; Chu Lu-Tao; Du Min |
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | A mathematical model of sandwich-type lateral flow immunoassay (LFIA) is established to describe the dynamic process of LFIA according to the biochemical principle of LFIA together with the convection-diffusion equations and the hydromagnetic equations. Based on the established model, the COMSOL software is utilized to simulate the dynamic process of LFIA. The simulation results not only demonstrate the relationships between the concentration of the sandwiched substance and the position or the time, but also analyze the influences of the initial concentrations of all substances and the structure on the performance ofLFIA system when the target analyte A is from 0 to 20 mol/L, reporter particle P is from 1 x 10(-2) mol/L to 1 x 10(3) mol/L and the porosity is from 0 to 1. Especially, within a certain concentration range, the increasing concentration of target analyte A and reporter particle P will enhance the quantitative performance of LFIA, and the porosity affects the result by controlling the flow rate of the test mixture and the material contact in the mixture. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/11578]  |
| 专题 | 深圳先进技术研究院_集成所 |
| 作者单位 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY |
| 推荐引用方式 GB/T 7714 | Zeng Nian-Yin,Zhu Pan-Pan,Li Yu-Rong,et al. Study on Mathematical Model and Simulation of Sandwich-type Lateral Flow Immunoassay.[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2017. |
| APA | Zeng Nian-Yin,Zhu Pan-Pan,Li Yu-Rong,Jiang Hai-Yan,Chu Lu-Tao,&Du Min.(2017).Study on Mathematical Model and Simulation of Sandwich-type Lateral Flow Immunoassay..CHINESE JOURNAL OF ANALYTICAL CHEMISTRY. |
| MLA | Zeng Nian-Yin,et al."Study on Mathematical Model and Simulation of Sandwich-type Lateral Flow Immunoassay.".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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