Post-Surgery Glioma Growth Modeling from Magnetic Resonance Images for Patients with Treatment.
文献类型：期刊论文
| 作者 | Elazab, Ahmed; Bai, Hongmin; Abdulazeem, Yousry M; Abdelhamid, Talaat; Zhou, Sijie; Wong, Kelvin K. L; Hu, Qingmao |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Reaction diffusion is the most common growth modelling methodology due to its simplicity and consistency with the biological tumor growth process. However, current extensions of the reaction diffusion model lack one or more of the following: efficient inclusion of treatments' effects, taking into account the viscoelasticity of brain tissues, and guaranteed stability of the numerical solution. We propose a new model to overcome the aforementioned drawbacks. Guided by directional information derived from diffusion tensor imaging, our model relates tissue heterogeneity with the absorption of the chemotherapy, adopts the linear-quadratic term to simulate the radiotherapy effect, employs Maxwell-Weichert model to incorporate brain viscoelasticity, and ensures the stability of the numerical solution. The performance is verified through experiments on synthetic and real MR images. Experiments on 9 MR datasets of patients with low grade gliomas undergoing surgery with different treatment regimens are carried out and validated using Jaccard score and Dice coefficient. The growth simulation accuracies of the proposed model are in ranges of [0.673 0.822] and [0.805 0.902] for Jaccard scores and Dice coefficients, respectively. The accuracies decrease up to 4% and 2.4% when ignoring treatment effects and the tensor information, while brain viscoelasticity has no significant impact on the accuracies. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/11959]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | SCIENTIFIC REPORTS |
| 推荐引用方式 GB/T 7714 | Elazab, Ahmed,Bai, Hongmin,Abdulazeem, Yousry M,et al. Post-Surgery Glioma Growth Modeling from Magnetic Resonance Images for Patients with Treatment.[J]. SCIENTIFIC REPORTS,2017. |
| APA | Elazab, Ahmed.,Bai, Hongmin.,Abdulazeem, Yousry M.,Abdelhamid, Talaat.,Zhou, Sijie.,...&Hu, Qingmao.(2017).Post-Surgery Glioma Growth Modeling from Magnetic Resonance Images for Patients with Treatment..SCIENTIFIC REPORTS. |
| MLA | Elazab, Ahmed,et al."Post-Surgery Glioma Growth Modeling from Magnetic Resonance Images for Patients with Treatment.".SCIENTIFIC REPORTS (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。