Protein-Modified CuS Nanotriangles: A Potential Multimodal Nanoplatform for In Vivo Tumor Photoacoustic/Magnetic Resonance Dual-Modal Imaging.
文献类型：期刊论文
| 作者 | Gao, Duyang; Sheng, Zonghai; Liu, Yubin; Hu, Dehong; Zhang, Jian; Zhang, Xuanjun; Zheng, Hairong; Yuan, Zhen |
| 刊名 | ADVANCED HEALTHCARE MATERIALS
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Controllable preparation of water-soluble multifunctional nanoprobes is of great significance for cancer early diagnosis. In this study, protein-modified hydrophilic copper sufide (CuS) nanotriangles with tunable absorption in the second near-infrared region are developed in the presence of halide ions. Further, gadolinium ions chelated diethylenetriaminepentaacetic acid is conjugated on it by using the unique characteristics of the protein-protected nanotriangles. Specifically, the as-obtained nanostructures are investigated as contrast agents for enhanced in vivo photoacoustic/magnetic resonance dual-modal tumor imaging. More importantly, in vitro and in vivo toxicity analysis are also performed, which show that the dual-modal nanoprobes are biocompatible for most of the cases. It is demonstrated that the novel as-prepared protein-modified nanotriangles are able to work as a nanoplatform to construct dual-modal nanoprobes, which paves a new avenue for improving the photoacoustic/magnetic resonance imaging contrast in cancer detection. It should be pointed out that other functional blocks may also be linked on it, which makes it a general method to design multifunctional nanoprobes. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12048]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | ADVANCED HEALTHCARE MATERIALS |
| 推荐引用方式 GB/T 7714 | Gao, Duyang,Sheng, Zonghai,Liu, Yubin,et al. Protein-Modified CuS Nanotriangles: A Potential Multimodal Nanoplatform for In Vivo Tumor Photoacoustic/Magnetic Resonance Dual-Modal Imaging.[J]. ADVANCED HEALTHCARE MATERIALS,2017. |
| APA | Gao, Duyang.,Sheng, Zonghai.,Liu, Yubin.,Hu, Dehong.,Zhang, Jian.,...&Yuan, Zhen.(2017).Protein-Modified CuS Nanotriangles: A Potential Multimodal Nanoplatform for In Vivo Tumor Photoacoustic/Magnetic Resonance Dual-Modal Imaging..ADVANCED HEALTHCARE MATERIALS. |
| MLA | Gao, Duyang,et al."Protein-Modified CuS Nanotriangles: A Potential Multimodal Nanoplatform for In Vivo Tumor Photoacoustic/Magnetic Resonance Dual-Modal Imaging.".ADVANCED HEALTHCARE MATERIALS (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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