A Fast Screening Protocol for Carotid Plaques Imaging Using 3D Multi-contrast MRI without Contrast Agent
文献类型：期刊论文
| 作者 | Liu Xin; Zhang Na; Zhang Lei; Yang Qi; Pei Anqi; Tong Xiaoxin; Chung Yiu-Cho |
| 刊名 | MAGNETIC RESONANCE IMAGING
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Purpose: To implement a fast (~15 minutes) MRI protocol for carotid plaque screening using 3D multi-contrast MRI sequences without contrast agent on a 3 Tesla MRI scanner. Materials and Methods: 7 healthy volunteers and 25 patients with clinically confirmed transient ischemic attack or suspected cerebrovascular ischemia were included in this study. The proposed protocol, including 3D T1-weighted and T2-weighted SPACE (variable-flip-angle 3D turbo spin echo), and T1-weighted magnetization prepared rapid acquisition gradient echo (MPRAGE) was performed first and was followed by 2D T1-weighted and T2-weighted turbo spin echo, and post-contrast T1-weighted SPACE sequences. Image quality, number of plaques, and vessel wall thicknesses measured at the intersection of the plaques were evaluated and compared between sequences. Results: Average examination time of the proposed protocol was 14.6 minutes. The average image quality scores of 3D T1-weighted, T2-weighted SPACE, and T1-weighted magnetization prepared rapid acquisition gradient echo were 3.69, 3.75, and 3.48, respectively. There was no significant difference in detecting the number of plaques and vulnerable plaques using pre-contrast 3D images with or without post-contrast T1-weighted SPACE. The 3D SPACE and 2D turbo spin echo sequences had excellent agreement (R = 0.96 for T1-weighted and 0.98 for T2-weighted, p<0.001) regarding vessel wall thickness measurements. Conclusion: The proposed protocol demonstrated the feasibility of attaining carotid plaque screening within a 15-minute scan, which provided sufficient anatomical coverage and critical diagnostic information. This protocol offers the potential for rapid and reliable screening for carotid plaques without contrast agent. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12061]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | MAGNETIC RESONANCE IMAGING |
| 推荐引用方式 GB/T 7714 | Liu Xin,Zhang Na,Zhang Lei,et al. A Fast Screening Protocol for Carotid Plaques Imaging Using 3D Multi-contrast MRI without Contrast Agent[J]. MAGNETIC RESONANCE IMAGING,2017. |
| APA | Liu Xin.,Zhang Na.,Zhang Lei.,Yang Qi.,Pei Anqi.,...&Chung Yiu-Cho.(2017).A Fast Screening Protocol for Carotid Plaques Imaging Using 3D Multi-contrast MRI without Contrast Agent.MAGNETIC RESONANCE IMAGING. |
| MLA | Liu Xin,et al."A Fast Screening Protocol for Carotid Plaques Imaging Using 3D Multi-contrast MRI without Contrast Agent".MAGNETIC RESONANCE IMAGING (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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