On the dynamics of StemBells: Microbubble-conjugated stem cells for ultrasound-controlled delivery.
文献类型：期刊论文
| 作者 | Kamp, Otto; Juffermans, Lynda J. M.; Naaijkens, Benno A.; Kokhuis, Tom J. A.; de Jong, Nico; Versluis, Michel; van der Steen, Antonius F. W. |
| 刊名 | APPLIED PHYSICS LETTERS
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | The use of stem cells for regenerative tissue repair is promising but hampered by the low number of cells delivered to the site of injury. To increase the delivery, we propose a technique in which stem cells are linked to functionalized microbubbles, creating echogenic complex dubbed StemBells. StemBells are highly susceptible to acoustic radiation force which can be employed after injection to push the StemBells locally to the treatment site. To optimally benefit from the delivery technique, a thorough characterization of the dynamics of StemBells during ultrasound exposure is needed. Using high-speed optical imaging, we study the dynamics of StemBells as a function of the applied frequency from which resonance curves were constructed. A theoretical model, based on a modified Rayleigh-Plesset type equation, captured the experimental resonance characteristics and radial dynamics in detail. Published by AIP Publishing. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12073]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | APPLIED PHYSICS LETTERS |
| 推荐引用方式 GB/T 7714 | Kamp, Otto,Juffermans, Lynda J. M.,Naaijkens, Benno A.,et al. On the dynamics of StemBells: Microbubble-conjugated stem cells for ultrasound-controlled delivery.[J]. APPLIED PHYSICS LETTERS,2017. |
| APA | Kamp, Otto.,Juffermans, Lynda J. M..,Naaijkens, Benno A..,Kokhuis, Tom J. A..,de Jong, Nico.,...&van der Steen, Antonius F. W..(2017).On the dynamics of StemBells: Microbubble-conjugated stem cells for ultrasound-controlled delivery..APPLIED PHYSICS LETTERS. |
| MLA | Kamp, Otto,et al."On the dynamics of StemBells: Microbubble-conjugated stem cells for ultrasound-controlled delivery.".APPLIED PHYSICS LETTERS (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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