Adjuvant Photothermal Therapy Inhibits Local Recurrences afterBreast-Conserving Surgery with Little Skin Damage
文献类型：期刊论文
| 作者 | Shouju Wang; Xingqun Ma; Xuhao Hong; Yingxia Chen; Ying Tian; Shuang Zhao; Wenfei Liu; Yuxia Tang; Ruizhi Zhao; Liang Song |
| 刊名 | ACS Nano
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Adjuvant treatments followed breast-conserving surgery (BCS) are essential to reduce the risk of local recurrences in patients with breast cancer. However, current adjuvant treatments are based on ionizing radiation, which brings radiation-induced damage and amplifies the risk of death. Here we explore the feasibility of using non-ionizing light to induce photothermal therapyas an adjuvant treatment to BCS. In an orthotopic breast cancer mice model, we demonstrate that adjuvant photothermal therapy (aPTT) decreases the incidence of local recurrences after BCS with no expense of cosmetic outcome. In comparison with conventional photothermaltherapy (cPTT), the technique used in aPTT provides more uniformly distributed light energy and less risk of skin burns and local recurrences. Overall, this work represents a departure from the traditional concept of using PTT as an alternative to surgery and reveals the potential of using PTT as an alternative to adjuvant radiation therapy, which is valuable especially for patients susceptible to radiation damage. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12113]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 作者单位 | ACS Nano |
| 推荐引用方式 GB/T 7714 | Shouju Wang, Xingqun Ma, Xuhao Hong,et al. Adjuvant Photothermal Therapy Inhibits Local Recurrences afterBreast-Conserving Surgery with Little Skin Damage[J]. ACS Nano,2017. |
| APA | Shouju Wang., Xingqun Ma., Xuhao Hong., Yingxia Chen., Ying Tian.,...& Guangming Lu.(2017).Adjuvant Photothermal Therapy Inhibits Local Recurrences afterBreast-Conserving Surgery with Little Skin Damage.ACS Nano. |
| MLA | Shouju Wang,et al."Adjuvant Photothermal Therapy Inhibits Local Recurrences afterBreast-Conserving Surgery with Little Skin Damage".ACS Nano (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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