Europium-phenolic network coated BaGdF5 nanocomposites for tri-modal computed tomography/magnetic resonance/luminescence imaging
文献类型：期刊论文
| 作者 | Wei Zhu; Shuang Liang; Jing Wang; Zhe Yang; Li Zhang; Tianmeng Yuan; Xu, Zushun; Xu, Haibo; Li, Penghui; Zushun Xu |
| 刊名 | JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Multifunctional nanocomposites based on BaGdF5 nanoparticles (NPs) and metal phenolic network (MPN) have been engineered as novel contrast agents for potential applications in X-ray computed tomography, magnetic resonance and luminescence imaging. The BaGdF5@MPN nanocomposites were synthesized at room temperature by coating BaGdF5 NPs with europiumphenolic network, which was obtained by the coordination of europium (III) with tannic acid (TA). The in vitro cytotoxicity assays against HepG2 cells revealed that the BaGdF5@MPN nanocomposites presented better cytocompatibility and lower cytotoxity than pure BaGdF5 NPs. In addition, vivid red and green luminescence can be observed by confocal laser scanning microscope (CLSM) from the BaGdF5@MPN nanocomposites laden HepG2 cells under the excitation of UV (390 nm) and visible light (440 nm), respectively. The longitudinal relaxivity value (r1) of the nanocomposites was 2.457mM−1s−1. Moreover, the nanocomoposites exhibited X-ray computed tomography (CT) and T1-weighted magnetic resonance (MR) imaging capacities, and the intensities of the enhanced signals of in vitro CT and MR images were proportional to the concentrations of the nanocomposites. These results indicated that the as-prepared BaGdF5@MPN nanocomposites are promising contrast agents for CT/MR/ luminescence imaging. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12294]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE |
| 推荐引用方式 GB/T 7714 | Wei Zhu,Shuang Liang,Jing Wang,et al. Europium-phenolic network coated BaGdF5 nanocomposites for tri-modal computed tomography/magnetic resonance/luminescence imaging[J]. JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE,2017. |
| APA | Wei Zhu.,Shuang Liang.,Jing Wang.,Zhe Yang.,Li Zhang.,...&Penghui Li.(2017).Europium-phenolic network coated BaGdF5 nanocomposites for tri-modal computed tomography/magnetic resonance/luminescence imaging.JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE. |
| MLA | Wei Zhu,et al."Europium-phenolic network coated BaGdF5 nanocomposites for tri-modal computed tomography/magnetic resonance/luminescence imaging".JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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