Stable and Multifunctional Dye-Modified Black Phosphorus Nanosheets for Near-Infrared Imaging-Guided Photothermal Therapy.
文献类型：期刊论文
| 作者 | Li, Zhibin ; Yu, Xue-Feng; Yang, Na ; Fu, Haidi ; Wu, Lie ; Cui, Haodong ; Zhou, Wenhua ; Wang, Jiahong ; Wang, Huaiyu ; Chu, Paul K. |
| 刊名 | CHEMISTRY OF MATERIALS
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Nanomedicines intergrating both therapy and diagnosis functions provide a promising strategy for anticancer treatment. As novel two-dimensional materials, black phosphorus nanosheets (BPs) possess unique properties for biomedical applications, pratically for photothermal therapy (PTT) of cancer, but their lack of air and water stability may hinder their application. Herein, a covalent functionalization strategy based on Nile Blue (NB) dye via diazonium chemistry is established to modify BPs, not only enhancing the stability of BPs but also rendering BPs via near infrared (NIR) fluorescence, forming a novel multifunctionalnanomedicine with both PTT and NIR imaging capabilities. In vitro tests demonstrate that the dye-modified BPs (named NB@BPs) have good biocompatibility and exhibit strong PTT and NIR imaging efficiency. In vivo experiments show that the NB@BPs,can mark the tumor site with red fluorescence and lead to efficient tumor ablation under NIR irradiation. These results reveal a potential BP-based nanomedicine with multiple fimctionalities that bode well for anticancer applications. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12307]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | CHEMISTRY OF MATERIALS |
| 推荐引用方式 GB/T 7714 | Li, Zhibin , Yu, Xue-Feng, Yang, Na ,et al. Stable and Multifunctional Dye-Modified Black Phosphorus Nanosheets for Near-Infrared Imaging-Guided Photothermal Therapy.[J]. CHEMISTRY OF MATERIALS,2017. |
| APA | Li, Zhibin ., Yu, Xue-Feng., Yang, Na ., Fu, Haidi ., Wu, Lie .,...& Tong, Liping .(2017).Stable and Multifunctional Dye-Modified Black Phosphorus Nanosheets for Near-Infrared Imaging-Guided Photothermal Therapy..CHEMISTRY OF MATERIALS. |
| MLA | Li, Zhibin ,et al."Stable and Multifunctional Dye-Modified Black Phosphorus Nanosheets for Near-Infrared Imaging-Guided Photothermal Therapy.".CHEMISTRY OF MATERIALS (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。