Unsupervised boundary delineation of spinal neural foramina using a multi-feature and adaptive spectral segmentation.
文献类型：期刊论文
| 作者 | He, Xiaoxu; Zhang, Heye; Landis, Mark; Sharma, Manas; Warrington, James; Li, Shuo |
| 刊名 | MEDICAL IMAGE ANALYSIS
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | As a common disease in the elderly, neural foramina stenosis (NFS) brings a significantly negative impact on the quality of life due to its symptoms including pain, disability, fall risk and depression. Accurate boundary delineation is essential to the clinical diagnosis and treatment of NFS. However, existing clinical routine is extremely tedious and inefficient due to the requirement of physicians' intensively manual delineation. Automated delineation is highly needed but faces big challenges from the complexity and variability in neural foramina images. In this paper, we propose a pure image-driven unsupervised boundary delineation framework for the automated neural foramina boundary delineation. This framework is based on a novel multi-feature and adaptive spectral segmentation (MFASS) algorithm. MFASS firstly utilizes the combination of region and edge features to generate reliable spectral features with a good separation between neural foramina and its surroundings, then estimates an optimal separation threshold for each individual image to separate neural foramina from its surroundings. This self-adjusted optimal separation threshold, estimated from spectral features, successfully overcome the diverse appearance and shape variations. With the robustness from the multi-feature fusion and the flexibility from the adaptively optimal separation threshold estimation, the proposed framework, based on MFASS, provides an automated and accurate boundary delineation. Validation was performed in 280 neural foramina MR images from 56 clinical subjects. Our method was benchmarked with manual boundary obtained by experienced physicians. Results demonstrate that the proposed method enjoys a high and stable consistency with experienced physicians (Dice: 90.58% +/- 2.79%; SMAD: 0.5657 +/- 0.1544 mm). Therefore, the proposed framework enables an efficient and accurate clinical tool in the diagnosis of neural foramina stenosis. (C) 2016 Elsevier B.V. All rights reserved. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12590]  |
| 专题 | 深圳先进技术研究院_数字所 |
| 作者单位 | MEDICAL IMAGE ANALYSIS |
| 推荐引用方式 GB/T 7714 | He, Xiaoxu,Zhang, Heye,Landis, Mark,et al. Unsupervised boundary delineation of spinal neural foramina using a multi-feature and adaptive spectral segmentation.[J]. MEDICAL IMAGE ANALYSIS,2017. |
| APA | He, Xiaoxu,Zhang, Heye,Landis, Mark,Sharma, Manas,Warrington, James,&Li, Shuo.(2017).Unsupervised boundary delineation of spinal neural foramina using a multi-feature and adaptive spectral segmentation..MEDICAL IMAGE ANALYSIS. |
| MLA | He, Xiaoxu,et al."Unsupervised boundary delineation of spinal neural foramina using a multi-feature and adaptive spectral segmentation.".MEDICAL IMAGE ANALYSIS (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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