Whole genome synthesis: from poliovirus to synthetic yeast
文献类型：期刊论文
| 作者 | Boeke Jef D.Boeke; Yang Huanming; Yuan Yinjing; Dai Junbiao; Cai Yizhi |
| 刊名 | Quantitative Biology
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | About thirty years ago when the human genome project(HGP) was first proposed, there was widespread disagreement on whether it was worth spending $3 billion to sequence a genome with only 3% coding sequences, which was potentially with enormous errors due to technical limitations at the time. However, it turned out to be successful, generating a return on investment to the US economy estimated at more than $796 billion. In addition, it led to a wave of biotechnology revolutions including ultra high-throughput sequencing techniques, long read sequencing, computational methodologies and others, which were not foreseen at the inception of the project. Ultimately it led to a better understanding of the fundamentals of life sciences and promises to provide enormous benefit to human health. Synthesis of a complete genome has encountered similar criticism, especially in the face of emerging techniques that could potentially be used to editing whole genomes. We envision the impact of writing genomes will be even larger than that of reading genomes. Also, the societal implications will also be more complicated and need to be handled with greater care. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12333]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | Quantitative Biology |
| 推荐引用方式 GB/T 7714 | Boeke Jef D.Boeke, Yang Huanming, Yuan Yinjing,et al. Whole genome synthesis: from poliovirus to synthetic yeast[J]. Quantitative Biology,2017. |
| APA | Boeke Jef D.Boeke, Yang Huanming, Yuan Yinjing,Dai Junbiao,& Cai Yizhi.(2017).Whole genome synthesis: from poliovirus to synthetic yeast.Quantitative Biology. |
| MLA | Boeke Jef D.Boeke,et al."Whole genome synthesis: from poliovirus to synthetic yeast".Quantitative Biology (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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