Design and chemical synthesis of eukaryotic chromosomes
文献类型：期刊论文
| 作者 | Yuan, Ying-Jin; Xie, Ze-Xiong; Liu, Duo; Li, Bing-Zhi; Zhao, Meng; Zeng, Bo-Xuan; Wu, Yi; Shen, Yue; Lin, Tao; Yang, Ping |
| 刊名 | Chemical Society reviews
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Following the discovery of the DNA double helix structure and the advancement of genome sequencing, we have entered a promising stage with regard to genome writing. Recently, a milestone breakthrough was achieved in the chemical synthesis of designer yeast chromosomes. Here, we review the systematic approaches to the de novo synthesis of designer eukaryotic chromosomes, with an emphasis on technologies and methodologies that enable design, building, testing and debugging. The achievement of chemically synthesized genomes with customized genetic features offers an opportunity to rebuild genome organization, remold biological functions and promote life evolution, which will be of great benefit for application in medicine and industrial manufacturing. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000417020300006 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12335]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | Chemical Society reviews |
| 推荐引用方式 GB/T 7714 | Yuan, Ying-Jin,Xie, Ze-Xiong,Liu, Duo,et al. Design and chemical synthesis of eukaryotic chromosomes[J]. Chemical Society reviews,2017. |
| APA | Yuan, Ying-Jin.,Xie, Ze-Xiong.,Liu, Duo.,Li, Bing-Zhi.,Zhao, Meng.,...&Yang, Huanming.(2017).Design and chemical synthesis of eukaryotic chromosomes.Chemical Society reviews. |
| MLA | Yuan, Ying-Jin,et al."Design and chemical synthesis of eukaryotic chromosomes".Chemical Society reviews (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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