Mineralization of a superficially porous microsphere scaffold via plasma modification.
文献类型：期刊论文
| 作者 | Cheng, Delin; Hou, Jie; Zhang, Fen; Shi, Xuetao; Cao, Xiaodong |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Mineralization on bone repair devices is beneficial for osteoconductivity and thus osteogenesis. Surface chemistry modification by plasma treatment can significantly improve mineralization. In this study, superficially porous poly(lactide-co-glycolide)/hydroxyapatite (PLGA/HA) microsphere scaffolds (PH) were processed by oxygen and ammonia plasma followed by incubation in simulated body fluids (SBF) for mineralization. The effect of plasma treatment and incubation time on the features of the mineralization layer was investigated. The results showed that novel porous mineralization layers were obtained on the unmodified PH (As-grown), oxygen pretreated PH (OPH) and ammonia pretreated PH (NPH). The mechanical property and superficially porous structures of scaffolds changed little after plasma treatment. However, OPH produced the most significant apatite layer with an increasing roughness with mineralization time. In contrast, As-grown just had a smooth mineralization layer. Moreover, the mineralization layer on As-grown was easy to peel off compared with those on OPH and NPH, demonstrating that plasma treatment could enhance the bonding force between apatite and the substrate surface. The surface chemical analysis proved that the difference in outcome of mineralization was because plasma treatment introduced additional polar domains onto the scaffolds. This work provided a promising mineralization material system for bone repair application. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12349]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | RSC ADVANCES |
| 推荐引用方式 GB/T 7714 | Cheng, Delin,Hou, Jie,Zhang, Fen,et al. Mineralization of a superficially porous microsphere scaffold via plasma modification.[J]. RSC ADVANCES,2017. |
| APA | Cheng, Delin,Hou, Jie,Zhang, Fen,Shi, Xuetao,&Cao, Xiaodong.(2017).Mineralization of a superficially porous microsphere scaffold via plasma modification..RSC ADVANCES. |
| MLA | Cheng, Delin,et al."Mineralization of a superficially porous microsphere scaffold via plasma modification.".RSC ADVANCES (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。