13-93 bioactive glass/alginate composite scaffolds 3D printed under mild conditions for bone regeneration.
文献类型：期刊论文
| 作者 | Luo, Guilin; Ma, Yufei; Cui, Xu; Jiang, Lixin; Wu, Mingming; Hu, Yang; Luo, Yanfeng; Pan, Haobo; Ruan, Changshun |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Composite scaffolds of type 13-93 bioactive glass (13-93 BG) and sodium alginate (SA), denoted 13-93 BG/ SA, in mass ratios of 0 : 4, 1 : 4, 2 : 4 and 4 : 4 were prepared for bone regeneration by 3D printing under mild conditions. All obtained scaffolds were completely interconnected. As the 13-93 BG/SA mass ratio increased from 0 : 4 to 4 : 4, the pore size improved from 340 +/- 27 to 530 +/- 27 mu m, porosity increased from 65.5 + 5.3 to 87.5 + 3.9% and shrinkage ratios decreased by half. Moreover, 13-93 BG incorporation improved the compressive strength and modulus of the SA scaffold, achieving highest values of 16.74 +/- 1.78 MPa and 79.49 +/- 7.38 MPa, respectively, in 13-93 BG/ SA with a 2 : 4 mass ratio. Furthermore, in vitro apatite mineralization, the release of bioactive ions (Mg2+ and SiO44 ) and a weakly alkaline pH were exhibited by scaffolds containing 13-93 BG, which further promoted the attachment, proliferation and osteogenic differentiation of rBMSCs on composite scaffolds. As a result, 3D-printed 13-93 BG/ SA scaffold was an ideal candidate for bone regeneration. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12350]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | RSC ADVANCES |
| 推荐引用方式 GB/T 7714 | Luo, Guilin,Ma, Yufei,Cui, Xu,et al. 13-93 bioactive glass/alginate composite scaffolds 3D printed under mild conditions for bone regeneration.[J]. RSC ADVANCES,2017. |
| APA | Luo, Guilin.,Ma, Yufei.,Cui, Xu.,Jiang, Lixin.,Wu, Mingming.,...&Ruan, Changshun.(2017).13-93 bioactive glass/alginate composite scaffolds 3D printed under mild conditions for bone regeneration..RSC ADVANCES. |
| MLA | Luo, Guilin,et al."13-93 bioactive glass/alginate composite scaffolds 3D printed under mild conditions for bone regeneration.".RSC ADVANCES (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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