Cell-mediated Strategy to Delivery Photosensitizer
文献类型：会议论文
| 作者 | Guanjun Deng; Lintao Cai; Ping Gong; Jiazheng Lai; Sanpeng Li; Ting Zhu; Zhihong Sun |
| 出版日期 | 2017 |
| 会议日期 | 2017 |
| 会议地点 | 中国北京 |
| 英文摘要 | Two of the challenges for clinical implementation of nano-therapeutic strategies are optimization of tumor targeting and clearance of the nanoagents in vivo. Macrophage serve as a “Trojan Horse” to delivery photosensitizer is attractive in therapeutic applications, especially the nearly impermeable biological barriers can be effectively circumvented. In this work, a cell-mediated therapy by transporting IR-780 within macrophage vehicles is described. The IR-780 with excellent near-infrared photothermal performance exhibit high macrophage uptake and negligible cytotoxicity by confocal microscopy, and the increased temperature of IR-780-laden-macrophages was higher than free IR-780. Thus, IR-780-laden-macrophages could be a desirable system for highly efficient near-infrared photothermal cancer therapy. |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/12394]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | 2017 |
| 推荐引用方式 GB/T 7714 | Guanjun Deng,Lintao Cai,Ping Gong,et al. Cell-mediated Strategy to Delivery Photosensitizer[C]. 见:. 中国北京. 2017. |
入库方式： OAI收割
来源：深圳先进技术研究院
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