Astrocytic Contributions to Synaptic and Learning Abnormalities in a Mouse Model of Fragile X Syndrome
文献类型：期刊论文
| 作者 | Hodges, Jennifer L; Yu, Xinzhu; Gilmore, Anthony; Bennett, Hannah; Tjia, Michelle; Perna, James F; Chen, Chia-Chien; Li, Xiang; Lu, Ju; Zuo, Yi |
| 刊名 | Biological Psychiatry
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | BACKGROUND: Fragile X syndrome (FXS) is the most common type of mental retardation attributable to a single-gene mutation. It is caused by FMR1 gene silencing and the consequent loss of its protein product, fragile X mental retardation protein. Fmr1 global knockout (KO) mice recapitulate many behavioral and synaptic phenotypes associated with FXS. Abundant evidence suggests that astrocytes are important contributors to neurological diseases. This study investigates astrocytic contributions to the progression of synaptic abnormalities and learning impairments associated with FXS. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/11901]  |
| 专题 | 深圳先进技术研究院_脑所 |
| 作者单位 | Biological Psychiatry |
| 推荐引用方式 GB/T 7714 | Hodges, Jennifer L, Yu, Xinzhu, Gilmore, Anthony,et al. Astrocytic Contributions to Synaptic and Learning Abnormalities in a Mouse Model of Fragile X Syndrome[J]. Biological Psychiatry,2017. |
| APA | Hodges, Jennifer L., Yu, Xinzhu., Gilmore, Anthony., Bennett, Hannah., Tjia, Michelle.,...& Zuo, Yi.(2017).Astrocytic Contributions to Synaptic and Learning Abnormalities in a Mouse Model of Fragile X Syndrome.Biological Psychiatry. |
| MLA | Hodges, Jennifer L,et al."Astrocytic Contributions to Synaptic and Learning Abnormalities in a Mouse Model of Fragile X Syndrome".Biological Psychiatry (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
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