中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
The Role of Semaphorin 3A in Bone Remodeling

文献类型:期刊论文

作者Huang, Shishu; Zhao, Zhihe; Li, Juan; Yang, Fan; Zhou, Zongke; Wu, Nan; Duan, Xin; Hao, Jin; Li, Zhenxia
刊名FRONTIERS IN CELLULAR NEUROSCIENCE
出版日期2017
文献子类期刊论文
英文摘要Bone remodeling occurs at the bone surface throughout adult life and associates bony quantity and quality. This process is a balance between the osteoblastic bone formation and osteoclastic bone resorption, which cross-talks together. Semaphorin 3A is a membrane-associated secreted protein and regarded as a diffusible axonal chemorepellent, which has been identified in the involvement of bone resorption and formation synchronously. However, the role of Semaphorin 3A in bone homeostasis and diseases remains elusive, in particular the association to osteoblasts and osteoclasts. In this review article, we summarize recent progress of Semaphorin 3A in the bone mass, homeostasis, and diseases and discuss the novel application of nerve-based bone regeneration. This will facilitate the understanding of Semaphorin 3A in skeletal biology and shed new light on the modulation and potential treatment in the bone disorders.
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语种英语
源URL[http://ir.siat.ac.cn:8080/handle/172644/11903]  
专题深圳先进技术研究院_脑所
作者单位FRONTIERS IN CELLULAR NEUROSCIENCE
推荐引用方式
GB/T 7714
Huang, Shishu,Zhao, Zhihe,Li, Juan,et al. The Role of Semaphorin 3A in Bone Remodeling[J]. FRONTIERS IN CELLULAR NEUROSCIENCE,2017.
APA Huang, Shishu.,Zhao, Zhihe.,Li, Juan.,Yang, Fan.,Zhou, Zongke.,...&Li, Zhenxia.(2017).The Role of Semaphorin 3A in Bone Remodeling.FRONTIERS IN CELLULAR NEUROSCIENCE.
MLA Huang, Shishu,et al."The Role of Semaphorin 3A in Bone Remodeling".FRONTIERS IN CELLULAR NEUROSCIENCE (2017).

入库方式: OAI收割

来源:深圳先进技术研究院

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