The Role of Semaphorin 3A in Bone Remodeling
文献类型:期刊论文
作者 | Huang, Shishu; Zhao, Zhihe; Li, Juan; Yang, Fan; Zhou, Zongke; Wu, Nan; Duan, Xin; Hao, Jin; Li, Zhenxia |
刊名 | FRONTIERS IN CELLULAR NEUROSCIENCE
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出版日期 | 2017 |
文献子类 | 期刊论文 |
英文摘要 | Bone remodeling occurs at the bone surface throughout adult life and associates bony quantity and quality. This process is a balance between the osteoblastic bone formation and osteoclastic bone resorption, which cross-talks together. Semaphorin 3A is a membrane-associated secreted protein and regarded as a diffusible axonal chemorepellent, which has been identified in the involvement of bone resorption and formation synchronously. However, the role of Semaphorin 3A in bone homeostasis and diseases remains elusive, in particular the association to osteoblasts and osteoclasts. In this review article, we summarize recent progress of Semaphorin 3A in the bone mass, homeostasis, and diseases and discuss the novel application of nerve-based bone regeneration. This will facilitate the understanding of Semaphorin 3A in skeletal biology and shed new light on the modulation and potential treatment in the bone disorders. |
URL标识 | 查看原文 |
语种 | 英语 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/11903] ![]() |
专题 | 深圳先进技术研究院_脑所 |
作者单位 | FRONTIERS IN CELLULAR NEUROSCIENCE |
推荐引用方式 GB/T 7714 | Huang, Shishu,Zhao, Zhihe,Li, Juan,et al. The Role of Semaphorin 3A in Bone Remodeling[J]. FRONTIERS IN CELLULAR NEUROSCIENCE,2017. |
APA | Huang, Shishu.,Zhao, Zhihe.,Li, Juan.,Yang, Fan.,Zhou, Zongke.,...&Li, Zhenxia.(2017).The Role of Semaphorin 3A in Bone Remodeling.FRONTIERS IN CELLULAR NEUROSCIENCE. |
MLA | Huang, Shishu,et al."The Role of Semaphorin 3A in Bone Remodeling".FRONTIERS IN CELLULAR NEUROSCIENCE (2017). |
入库方式: OAI收割
来源:深圳先进技术研究院
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