Piriform cortical glutamatergic and GABAergic neurons express coordinated plasticity for whisker-induced odor recall
文献类型：期刊论文
| 作者 | Liu, Yahui; Wang, Jin-Hui; Wang, Liping; Lu, Wei; Feng, Jing; Fan, Ruichen; Zhao, Shidi; Ge, Rongjing; Huang, Li; Wen, Bo |
| 刊名 | ONCOTARGET
 |
| 出版日期 | 2017 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Neural plasticity occurs in learning and memory. Coordinated plasticity at glutamatergic and GABAergic neurons during memory formation remains elusive, which we investigate in a mouse model of associative learning by cellular imaging and electrophysiology. Paired odor and whisker stimulations lead to whisker- induced olfaction response. In mice that express this cross-modal memory, the neurons in the piriform cortex are recruited to encode newly acquired whisker signal alongside innate odor signal, and their response patterns to these associated signals are different. There are emerged synaptic innervations from barrel cortical neurons to piriform cortical neurons from these mice. These results indicate the recruitment of associative memory cells in the piriformcortex after associative memory. In terms of the structural and functional plasticity at these associative memory cells in the piriform cortex, glutamatergicneurons and synapses are upregulated, GABAergic neurons and synapses are downregulated as well as their mutual innervations are refined in the coordinated manner. Therefore, the associated activations of sensory cortices triggered by their input signals induce the formation of their mutual synapse innervations, the recruitment of associative memory cells and the coordinated plasticity between the GABAergic and glutamatergic neurons, which work forassociative memory cells to encode cross-modal associated signals in their integration, associative storage and distinguishable retrieval. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/11920]  |
| 专题 | 深圳先进技术研究院_脑所 |
| 作者单位 | ONCOTARGET |
| 推荐引用方式 GB/T 7714 | Liu, Yahui,Wang, Jin-Hui,Wang, Liping,et al. Piriform cortical glutamatergic and GABAergic neurons express coordinated plasticity for whisker-induced odor recall[J]. ONCOTARGET,2017. |
| APA | Liu, Yahui.,Wang, Jin-Hui.,Wang, Liping.,Lu, Wei.,Feng, Jing.,...&Gao, Zilong.(2017).Piriform cortical glutamatergic and GABAergic neurons express coordinated plasticity for whisker-induced odor recall.ONCOTARGET. |
| MLA | Liu, Yahui,et al."Piriform cortical glutamatergic and GABAergic neurons express coordinated plasticity for whisker-induced odor recall".ONCOTARGET (2017). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。