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Asymmetric Michael addition of arylthiols to alpha,beta-unsaturated carbonyl compounds catalyzed by bifunctional organocatalysts
文献类型：期刊论文
| 作者 | Li, BJ; Jiang, L; Liu, M; Chen, YC; Ding, LS; Wu, Y; Chen, YC, Sichuan Univ, W China Sch Pharm, Dept Med Chem, Chengdu 610041, Peoples R China. |
| 刊名 | SYNLETT
 |
| 出版日期 | 2005 |
| 期号 | 4页码:603_606 |
| 关键词 | Bifunctional Organocatalyst Thiourea Hydrogen Bonding Asymmetric Michael Addition Asymmetric Protonation |
| ISSN号 | 0936-5214 |
| 产权排序 | 2 |
| 英文摘要 | Bifunctional chiral organocatalysts comprising thiourea and tertiary amine groups were synthesized. They act as efficient catalysts for asymmetric Michael addition of arylthiols to alpha,beta-unsaturated carbonyl compounds. Enantioselectivity up to 85% has been achieved. Asymmetric alpha-protonation reaction (up to 60% ee) can be obtained in the presence of the bifunctional catalyst. |
| 学科主题 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000227583700010 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/17623]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Chen, YC, Sichuan Univ, W China Sch Pharm, Dept Med Chem, Chengdu 610041, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Li, BJ,Jiang, L,Liu, M,et al. Asymmetric Michael addition of arylthiols to alpha,beta-unsaturated carbonyl compounds catalyzed by bifunctional organocatalysts[J]. SYNLETT,2005(4):603_606. |
| APA | Li, BJ.,Jiang, L.,Liu, M.,Chen, YC.,Ding, LS.,...&Chen, YC, Sichuan Univ, W China Sch Pharm, Dept Med Chem, Chengdu 610041, Peoples R China..(2005).Asymmetric Michael addition of arylthiols to alpha,beta-unsaturated carbonyl compounds catalyzed by bifunctional organocatalysts.SYNLETT(4),603_606. |
| MLA | Li, BJ,et al."Asymmetric Michael addition of arylthiols to alpha,beta-unsaturated carbonyl compounds catalyzed by bifunctional organocatalysts".SYNLETT .4(2005):603_606. |
入库方式： OAI收割
来源：成都生物研究所
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