Dioscorea opposita reverses dexamethasone induced insulin resistance
文献类型：期刊论文
| 作者 | Gao, XP; Li, BG; Jiang, HW; Liu, FL; Xu, DY; Liu, ZR; Gao, XP, Di Ao Pharmaceut Grp, Inst Mat Med, Chengdu 610041, Peoples R China. |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2007 |
| 卷号 | 78期号:1页码:12_15 |
| 关键词 | Dioscorea Opposita Insulin Resistance Dexamethasone 3t3-l1 Adipocytes Glut4 |
| ISSN号 | 0367-326X |
| 产权排序 | 2 |
| 英文摘要 | The effects of Dioscorea opposita (huai shan yao, HSY) on dexamethasone-induced insulin resistance were investigated in vitro and in vivo. D. opposita extract reduced significantly the blood insulin and glucose levels in dexamethasone-induced diabetic rats. In vitro, HSY significantly enhanced insulin-stimulated glucose uptake in 3T3-L1 adipocytes. Moreover, HSY increase the mRNA expression of GLUT4 glucose transporter in 3T3-L1 adipocytes. These data suggest that D. opposita has insulin sensitivity that is associated with the regulation of GLUT4 expression. (c) 2006 Elsevier B.V. All rights reserved. |
| 学科主题 | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000243695900003 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/17931]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Gao, XP, Di Ao Pharmaceut Grp, Inst Mat Med, Chengdu 610041, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Gao, XP,Li, BG,Jiang, HW,et al. Dioscorea opposita reverses dexamethasone induced insulin resistance[J]. FITOTERAPIA,2007,78(1):12_15. |
| APA | Gao, XP.,Li, BG.,Jiang, HW.,Liu, FL.,Xu, DY.,...&Gao, XP, Di Ao Pharmaceut Grp, Inst Mat Med, Chengdu 610041, Peoples R China..(2007).Dioscorea opposita reverses dexamethasone induced insulin resistance.FITOTERAPIA,78(1),12_15. |
| MLA | Gao, XP,et al."Dioscorea opposita reverses dexamethasone induced insulin resistance".FITOTERAPIA 78.1(2007):12_15. |
入库方式： OAI收割
来源：成都生物研究所
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