Sculponins A-C, three new 6,7-seco-ent-kauranoids from Isodon sculponeatus
文献类型:期刊论文
作者 | Li, LM; Li, GY; Ding, LS; Lei, C; Yang, LB; Zhao, Y; Weng, ZY; Li, SH; Huang, SX; Xiao, WL |
刊名 | TETRAHEDRON LETTERS
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出版日期 | 2007 |
卷号 | 48期号:52页码:9100_9103 |
ISSN号 | 0040-4039 |
产权排序 | 3 |
英文摘要 | Three new 6,7-seco-eni-kauranoids (1-3) were isolated and structures were elucidated from Isodon sculponeatus. Diterpenoids 1-3 possessing multicyclic skeletons formed via oxygen atoms are all unprecedented among ent-kauranes. Compound I displayed significant cytotoxic activity against K562, A549, and HepG2 human tumor cell lines, with IC50 values of 1.4, 2.3, and 2.0 mu M, respectively, equal to the positive control. Plausible pathways for the biosynthesis of I and 2 from one related diterpenoid were also postulated. (C) 2007 Elsevier Ltd. All rights reserved. |
学科主题 | Chemistry, Organic |
语种 | 英语 |
WOS记录号 | WOS:000251846400008 |
公开日期 | 2011-07-08 |
源URL | [http://210.75.237.14/handle/351003/17971] ![]() |
专题 | 成都生物研究所_天然产物研究 |
通讯作者 | Sun, HD, Chinese Acad Sci, Kunming Inst Bot, State Key LPhytochem & Plant Resources W China, Kunming 650204, Peoples R China. |
推荐引用方式 GB/T 7714 | Li, LM,Li, GY,Ding, LS,et al. Sculponins A-C, three new 6,7-seco-ent-kauranoids from Isodon sculponeatus[J]. TETRAHEDRON LETTERS,2007,48(52):9100_9103. |
APA | Li, LM.,Li, GY.,Ding, LS.,Lei, C.,Yang, LB.,...&Sun, HD, Chinese Acad Sci, Kunming Inst Bot, State Key LPhytochem & Plant Resources W China, Kunming 650204, Peoples R China..(2007).Sculponins A-C, three new 6,7-seco-ent-kauranoids from Isodon sculponeatus.TETRAHEDRON LETTERS,48(52),9100_9103. |
MLA | Li, LM,et al."Sculponins A-C, three new 6,7-seco-ent-kauranoids from Isodon sculponeatus".TETRAHEDRON LETTERS 48.52(2007):9100_9103. |
入库方式: OAI收割
来源:成都生物研究所
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