Using small molecules on surfaces to control cell adhesion
文献类型：期刊论文
| 作者 | Liu, DB; Xie, YY; Shao, HW; Jiang, XY; Liu, DB, Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China. |
| 刊名 | PROGRESS IN CHEMISTRY
 |
| 出版日期 | 2007 |
| 卷号 | 19期号:12页码:1965_1971 |
| 关键词 | Cell Adhesion Cell Motility Surface Patterning Inert Surfaces Soft Lithography Microfluidic Channels |
| ISSN号 | 1005-281X |
| 其他题名 | 利用表面上的小分子控制细胞黏附 |
| 产权排序 | 1 |
| 英文摘要 | Cell adhesion is an important physiological process, most types of metazoic cells rely on adhesion to surfaces to carry out their functions. The adhesion of mammalian cells requires the presence of surface- immobilized molecules as ligands, in most cases, proteins or peptide mimics thereof, that bind to receptors on the cell membrane. The binding between these ligands and receptors promotes the adhesion of cells. Polyethyleneglycol (PEG) can resist cell adhesion. We use these small molecules to modulate cell adhesion on surfaces. Cell motility Is a dynamic process in which the binding between extracellular ligands and receptors on cell membrane undergo regulation in appropriate time and space. This review introduces several newly developed tools using small molecules on surfaces and microfabrication to control cell adhesion and motility. |
| 学科主题 | Chemistry, Multidisciplinary |
| 语种 | 中文 |
| WOS记录号 | WOS:000251957400015 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/17993]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Liu, DB, Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Liu, DB,Xie, YY,Shao, HW,et al. Using small molecules on surfaces to control cell adhesion[J]. PROGRESS IN CHEMISTRY,2007,19(12):1965_1971. |
| APA | Liu, DB,Xie, YY,Shao, HW,Jiang, XY,&Liu, DB, Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China..(2007).Using small molecules on surfaces to control cell adhesion.PROGRESS IN CHEMISTRY,19(12),1965_1971. |
| MLA | Liu, DB,et al."Using small molecules on surfaces to control cell adhesion".PROGRESS IN CHEMISTRY 19.12(2007):1965_1971. |
入库方式： OAI收割
来源：成都生物研究所
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