Volvalerenone A, a new type of mononorsesquiterpenoid with an unprecedented 3,12-oxo bridge from Valeriana officinalis
文献类型：期刊论文
| 作者 | Wang, Peng-Cheng; Ran, Xin-Hui; Chen, Rui; Li, Liang-Chun; Xiong, Shan-Shan; Liu, Yu-Qing; Luo, Huai-Rong; Zhou, Jun; Zhao, You-Xing; Zhou, J, Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2010 |
| 卷号 | 51期号:41页码:5451-5453 |
| 关键词 | Valeriana Officinalis Valerianacae Mononorsesquiterpenoid Volvalerenone a Ache Inhibitory Activity |
| ISSN号 | 0040-4039 |
| 产权排序 | 4 |
| 英文摘要 | Volvalerenone A (1), a new type of mononorsesquiterpenoid with an unprecedented 5/6/6 tricyclic ring system, was isolated from the roots of Valeriana officinalis, the official species of valerian used in Europe. The structure of volvalerenone A was elucidated based on its spectroscopic and single-crystal X-ray crystallography data. The absolute configuration was assigned by the computational method. A possible bio-synthetic pathway of volvalerenone A was also proposed. Preliminary biological studies showed that volvalerenone A had weak inhibitory activity on acetylcholine esterase (AChE), and no enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells was observed at 50 mu M. (C) 2010 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000282381000026 |
| 资助机构 | State Key Laboratory of Phytochemistry and Plant Resources in West China [P2008-ZZ22]; Natural Science foundation of Yunnan [2008CD 159] ; State Key Laboratory of Phytochemistry and Plant Resources in West China [P2008-ZZ22]; Natural Science foundation of Yunnan [2008CD 159] ; State Key Laboratory of Phytochemistry and Plant Resources in West China [P2008-ZZ22]; Natural Science foundation of Yunnan [2008CD 159] ; State Key Laboratory of Phytochemistry and Plant Resources in West China [P2008-ZZ22]; Natural Science foundation of Yunnan [2008CD 159] |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/18453]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Zhou, J, Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Peng-Cheng,Ran, Xin-Hui,Chen, Rui,et al. Volvalerenone A, a new type of mononorsesquiterpenoid with an unprecedented 3,12-oxo bridge from Valeriana officinalis[J]. TETRAHEDRON LETTERS,2010,51(41):5451-5453. |
| APA | Wang, Peng-Cheng.,Ran, Xin-Hui.,Chen, Rui.,Li, Liang-Chun.,Xiong, Shan-Shan.,...&Zhou, J, Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China.(2010).Volvalerenone A, a new type of mononorsesquiterpenoid with an unprecedented 3,12-oxo bridge from Valeriana officinalis.TETRAHEDRON LETTERS,51(41),5451-5453. |
| MLA | Wang, Peng-Cheng,et al."Volvalerenone A, a new type of mononorsesquiterpenoid with an unprecedented 3,12-oxo bridge from Valeriana officinalis".TETRAHEDRON LETTERS 51.41(2010):5451-5453. |
入库方式： OAI收割
来源：成都生物研究所
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