BrOnsted-Acid-Catalyzed Substrate-Controlled and Site-Selective Friedel-Crafts Alkylation: A New Strategy for Post-Modification of 1,2-Dihydroquinolines
文献类型：期刊论文
| 作者 | Huang, J; Li, GX; Yang, GB; Zhao, JZ; Tang, Z; Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China. |
| 刊名 | ASIAN JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 6期号:12页码:1741-1744 |
| 关键词 | Alkylation Asymmetric Catalysis Enantioselectivity Regioselectivity Synthetic Methods |
| DOI | 10.1002/ajoc.201700438 |
| 产权排序 | 1 |
| 文献子类 | Article |
| 英文摘要 | A variety of C3-, C6-, C8- and C13-functionalized 1,2-dihidroquinolines (1,2-DHQs) have been prepared through post-modification of simple 1,2-DHQs by regioselective Friedel-Crafts alkylations. Several commonly used electrophiles such as 3-indolylmethanol derivatives, nitroolefins, 1,4-benzoquinones, aromatic aldehydes and ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline were rationally used to afford the corresponding 1,2-DHQs with high yield and regioselectivity. The regioselectivity of the reaction appears to be governed by the substituents of the 1,2-DHQ substrates. |
| 学科主题 | Chemistry |
| 语种 | 英语 |
| 资助机构 | This work was supported financially by the Natural Science Foundation of China (21402188) and Natural Science Foundation of Sichuan province, China (2017JY0055). ; Natural Science Foundation of China [21402188] ; This work was supported financially by the Natural Science Foundation of China (21402188) and Natural Science Foundation of Sichuan province, China (2017JY0055). ; Natural Science Foundation of China [21402188] ; Natural Science Foundation of Sichuan province, China [2017JY0055] ; Natural Science Foundation of Sichuan province, China [2017JY0055] ; This work was supported financially by the Natural Science Foundation of China (21402188) and Natural Science Foundation of Sichuan province, China (2017JY0055). ; Natural Science Foundation of China [21402188] ; This work was supported financially by the Natural Science Foundation of China (21402188) and Natural Science Foundation of Sichuan province, China (2017JY0055). ; Natural Science Foundation of China [21402188] ; Natural Science Foundation of Sichuan province, China [2017JY0055] ; Natural Science Foundation of Sichuan province, China [2017JY0055] |
| 源URL | [http://210.75.237.14/handle/351003/29203]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Li, GX; Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Huang, J,Li, GX,Yang, GB,et al. BrOnsted-Acid-Catalyzed Substrate-Controlled and Site-Selective Friedel-Crafts Alkylation: A New Strategy for Post-Modification of 1,2-Dihydroquinolines[J]. ASIAN JOURNAL OF ORGANIC CHEMISTRY,2017,6(12):1741-1744. |
| APA | Huang, J,Li, GX,Yang, GB,Zhao, JZ,Tang, Z,&Tang, Z .(2017).BrOnsted-Acid-Catalyzed Substrate-Controlled and Site-Selective Friedel-Crafts Alkylation: A New Strategy for Post-Modification of 1,2-Dihydroquinolines.ASIAN JOURNAL OF ORGANIC CHEMISTRY,6(12),1741-1744. |
| MLA | Huang, J,et al."BrOnsted-Acid-Catalyzed Substrate-Controlled and Site-Selective Friedel-Crafts Alkylation: A New Strategy for Post-Modification of 1,2-Dihydroquinolines".ASIAN JOURNAL OF ORGANIC CHEMISTRY 6.12(2017):1741-1744. |
入库方式： OAI收割
来源：成都生物研究所
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