Re-characterization of hammerhead ribozymes as molecular tools for intermolecular RNA cleavage
文献类型：期刊论文
| 作者 | Huang, X; Cui, X; Dong, J; Du, F; Zhao, YY; Pu, QL; Tang, Z; Liu, GT; Tang, Z (reprint author), Univ Chinese Acad Sci, Nat Prod Res Ctr, Chengdu Inst Biol, Chengdu 610041, Sichuan, Peoples R China. |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 15期号:21页码:4681-4685 |
| DOI | 10.1039/c7ob00995j |
| 产权排序 | 1 |
| 文献子类 | Article |
| 英文摘要 | A new guideline for the construction of hammerhead ribozymes to achieve trans-cleavage of a single-stranded RNA molecule was developed. The sequence rule of the HHRz cleavage site was highly recommended to be "DWH" with an optimal binding arm length of 8-9nt, which diverged from the former rule of "NUX". |
| 学科主题 | Chemistry |
| 语种 | 英语 |
| 资助机构 | We are grateful to the National Natural Sciences Foundation of China (Grant No. 21322208 and 21572222) and the West Light Foundation of The Chinese Academy of Sciences (Y4C3021100). ; National Natural Sciences Foundation of China [21322208, 21572222] ; We are grateful to the National Natural Sciences Foundation of China (Grant No. 21322208 and 21572222) and the West Light Foundation of The Chinese Academy of Sciences (Y4C3021100). ; National Natural Sciences Foundation of China [21322208, 21572222] ; West Light Foundation of The Chinese Academy of Sciences [Y4C3021100] ; West Light Foundation of The Chinese Academy of Sciences [Y4C3021100] ; We are grateful to the National Natural Sciences Foundation of China (Grant No. 21322208 and 21572222) and the West Light Foundation of The Chinese Academy of Sciences (Y4C3021100). ; National Natural Sciences Foundation of China [21322208, 21572222] ; We are grateful to the National Natural Sciences Foundation of China (Grant No. 21322208 and 21572222) and the West Light Foundation of The Chinese Academy of Sciences (Y4C3021100). ; National Natural Sciences Foundation of China [21322208, 21572222] ; West Light Foundation of The Chinese Academy of Sciences [Y4C3021100] ; West Light Foundation of The Chinese Academy of Sciences [Y4C3021100] |
| 源URL | [http://210.75.237.14/handle/351003/29233]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Tang, Z (reprint author), Univ Chinese Acad Sci, Nat Prod Res Ctr, Chengdu Inst Biol, Chengdu 610041, Sichuan, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Huang, X,Cui, X,Dong, J,et al. Re-characterization of hammerhead ribozymes as molecular tools for intermolecular RNA cleavage[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2017,15(21):4681-4685. |
| APA | Huang, X.,Cui, X.,Dong, J.,Du, F.,Zhao, YY.,...&Tang, Z .(2017).Re-characterization of hammerhead ribozymes as molecular tools for intermolecular RNA cleavage.ORGANIC & BIOMOLECULAR CHEMISTRY,15(21),4681-4685. |
| MLA | Huang, X,et al."Re-characterization of hammerhead ribozymes as molecular tools for intermolecular RNA cleavage".ORGANIC & BIOMOLECULAR CHEMISTRY 15.21(2017):4681-4685. |
入库方式： OAI收割
来源：成都生物研究所
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