Three new labdane diterpenes from Loxocalyx urticifolius
文献类型：期刊论文
| 作者 | Guo, DL; Zhao, M; Zhou, Y (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Biodivers Conservat Key Lab Sichuan Prov, Chengdu 610041, PR, Peoples R China.; Zhou, Y (reprint author), Chinese Acad Sci, Chengdu Inst Biol, CAS Key Lab Mt Ecol Restorat & Bioresource Utiliz, Chengdu 610041, PR, Peoples R China.; Zhou, Y; Ding, LS; Chen, L; Gu, YC; Yuan, LY |
| 刊名 | PHYTOCHEMISTRY LETTERS
 |
| 出版日期 | 2017 |
| 卷号 | 19期号:2017页码:55-59 |
| 关键词 | Loxocalyx Urticifolius Lamiaceae Labdane Diterpene Cytotoxic Activity |
| DOI | 10.1016/j.phytol.2016.11.010 |
| 产权排序 | 1 |
| 文献子类 | Article |
| 英文摘要 | Three new labdane diterpenes, namely loxocalyxin D (1), loxocalyxin E (2) and 13-epiloxocalyxin E (3), were isolated from the whole plants of Loxocalyx urticifolius Hemsl. Their structures were elucidated by extensive spectral analysis and chemical methods. The absolute configuration of loxocalyxin D (1) was confirmed by X-ray crystallographic analysis. The cytotoxic activities of the isolated labdane diterpenes were evaluated against the four human cancer cell lines A549, HepG2, HL-60 and MCF-7. 13-epiloxocalyxin E (3) exhibited selective cytotoxicity against A549 and MCF-7 with the IC50 values of 22.4 and 47.3 mM, respectively. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved. |
| 学科主题 | Plant Sciences ; Pharmacology & Pharmacy |
| 项目编号 | 中国科学院山地生态恢复与生物资源利用重点实验室 |
| 语种 | 英语 |
| 资助机构 | This work was financially supported grants from the National Natural Sciences Foundation of China (21402157, 21572219 and 21572221) and a Syngenta Postgraduate Fellowship awarded to Min Zhao. ; National Natural Sciences Foundation of China [21402157, 21572219, 21572221] ; This work was financially supported grants from the National Natural Sciences Foundation of China (21402157, 21572219 and 21572221) and a Syngenta Postgraduate Fellowship awarded to Min Zhao. ; National Natural Sciences Foundation of China [21402157, 21572219, 21572221] ; Syngenta Postgraduate Fellowship award ; Syngenta Postgraduate Fellowship award ; This work was financially supported grants from the National Natural Sciences Foundation of China (21402157, 21572219 and 21572221) and a Syngenta Postgraduate Fellowship awarded to Min Zhao. ; National Natural Sciences Foundation of China [21402157, 21572219, 21572221] ; This work was financially supported grants from the National Natural Sciences Foundation of China (21402157, 21572219 and 21572221) and a Syngenta Postgraduate Fellowship awarded to Min Zhao. ; National Natural Sciences Foundation of China [21402157, 21572219, 21572221] ; Syngenta Postgraduate Fellowship award ; Syngenta Postgraduate Fellowship award |
| 源URL | [http://210.75.237.14/handle/351003/29251]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Zhou, Y (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Biodivers Conservat Key Lab Sichuan Prov, Chengdu 610041, PR, Peoples R China.; Zhou, Y (reprint author), Chinese Acad Sci, Chengdu Inst Biol, CAS Key Lab Mt Ecol Restorat & Bioresource Utiliz, Chengdu 610041, PR, Peoples R China.; Ding, LS |
| 推荐引用方式 GB/T 7714 | Guo, DL,Zhao, M,Zhou, Y ,et al. Three new labdane diterpenes from Loxocalyx urticifolius[J]. PHYTOCHEMISTRY LETTERS,2017,19(2017):55-59. |
| APA | Guo, DL.,Zhao, M.,Zhou, Y .,Zhou, Y .,Zhou, Y.,...&Yuan, LY.(2017).Three new labdane diterpenes from Loxocalyx urticifolius.PHYTOCHEMISTRY LETTERS,19(2017),55-59. |
| MLA | Guo, DL,et al."Three new labdane diterpenes from Loxocalyx urticifolius".PHYTOCHEMISTRY LETTERS 19.2017(2017):55-59. |
入库方式： OAI收割
来源：成都生物研究所
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